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@article{Orletti:2021:10.1016/j.bjid.2021.101631,
author = {Orletti, MPS and Assone, T and Sarnaglia, GD and Martins, ML and Rosadas, C and Casseb, J and Taylor, G and Ferreira-Filho, JB and Pereira, FEL and Miranda, AE},
doi = {10.1016/j.bjid.2021.101631},
journal = {Brazilian Journal of Infectious Diseases},
title = {Prevalence of infection by human T Cell lymphotropic viruses (HTLV-1/2) in adult population in Vitoria-ES},
url = {http://dx.doi.org/10.1016/j.bjid.2021.101631},
volume = {25},
year = {2021}
}
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TY  - JOUR
AB  - Introduction: Brazil has a high number of HTLV-1/2 infections which are unequally distributed in the country. Most prevalence studies have focused on specific populations, such as blood donors and pregnant women. Some areas, for example the state of Bahia, have robust information about HTLV-1/2 infection, however there is no information available about this infection in the general population of Vitória, Espírito Santo, Brazil. Objective: To determine the prevalence of HTLV-1/2 infection in adults from the municipality of Vitoria, ES. Methods: A cross sectional study was performed from September 2010 to December 2011, in individuals of both sexes, aged 18 or older living in Vitória-ES. Venous blood samples were collected and tested for anti-HTLV-1/2 antibodies by chemiluminescent immunoassay (CMIA). Individuals with CMIA reactive results were submitted to a new blood collection for retesting by CMIA, followed by PCR to confirm infection and discriminate the viral type. Results: From 1502 tested samples, eight were reactive in CMIA and all were confirmed by PCR. Therefore, the prevalence of HTLV-1/2 was 0.53% (8/1502, 95% CI: 0.2–1.0%). The infection rate was 0.7% in men (5/711, 95% CI: 0.17–1.51%), and 0.38% in women (3/791, 95% CI: 0–0.81%). Conclusions: The prevalence of HTLV-1/2 infection was 0.53% (8/1502; 95% CI: 0.2–0.9%). Confirmatory test using real-time PCR (qPCR) identified seven individuals positive for HTLV-1 and one for HTLV-2. Considering the risk of infected individuals to develop high morbidity and mortality diseases, it would be important to implement public health policies aimed at stopping transmission of these viruses in this municipality.
AU  - Orletti,MPS
AU  - Assone,T
AU  - Sarnaglia,GD
AU  - Martins,ML
AU  - Rosadas,C
AU  - Casseb,J
AU  - Taylor,G
AU  - Ferreira-Filho,JB
AU  - Pereira,FEL
AU  - Miranda,AE
DO  - 10.1016/j.bjid.2021.101631
PY  - 2021///
SN  - 1413-8670
TI  - Prevalence of infection by human T Cell lymphotropic viruses (HTLV-1/2) in adult population in Vitoria-ES
T2  - Brazilian Journal of Infectious Diseases
UR  - http://dx.doi.org/10.1016/j.bjid.2021.101631
UR  - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000724926900007&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR  - https://www.sciencedirect.com/science/article/pii/S1413867021001008
VL  - 25
ER  -
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