BibTex format
@article{Arnold:2016:10.1016/j.jinf.2016.12.005,
author = {Arnold, A and Cooke, GS and Kon, OM and Dedicoat, M and Lipman, M and Loyse, A and Butcher, PD and Ster, IC and Harrison, TS},
doi = {10.1016/j.jinf.2016.12.005},
journal = {Journal of Infection},
pages = {260--271},
title = {Drug resistant TB: UK multicentre study (DRUMS): Treatment, management and outcomes in London and West Midlands 2008-2014},
url = {http://dx.doi.org/10.1016/j.jinf.2016.12.005},
volume = {74},
year = {2016}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Objectives: Detailed information regarding treatment practices and outcomes ofMDR-TB treatment in the UK is required as a baseline for care improvements.Methods: 100 consecutive cases between 2008 and 2014 were reviewed retrospectively at 4MDR-TB treatment centres in England to obtain information on drug treatment choices, hospitaladmission duration and outcomes for MDR-TB.Results: Initial hospital admission was long, median 62.5 (IQR 20e106, n Z 92) days, and 13%(12/92) of patients lost their home during this period. Prolonged admission was associated withpulmonary cases, cavities on chest radiograph, a public health policy of waiting for sputum cultureconversion (CC) and loss of the patient’s home. Sputum CC occurred at a median of 33.5(IQR 16e55, n Z 46) days. Treatment success was high (74%, 74/100) and mortality low (1%, 1/100). A significant proportion of the cohort had “neutral” results due to deportation and transferoverseas (12%, (12/100)). 14% (14/100) had negative outcomes for which poor adherencewas the main reason (62%, 9/14).
AU - Arnold,A
AU - Cooke,GS
AU - Kon,OM
AU - Dedicoat,M
AU - Lipman,M
AU - Loyse,A
AU - Butcher,PD
AU - Ster,IC
AU - Harrison,TS
DO - 10.1016/j.jinf.2016.12.005
EP - 271
PY - 2016///
SN - 0163-4453
SP - 260
TI - Drug resistant TB: UK multicentre study (DRUMS): Treatment, management and outcomes in London and West Midlands 2008-2014
T2 - Journal of Infection
UR - http://dx.doi.org/10.1016/j.jinf.2016.12.005
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000397263200005&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
VL - 74
ER -