Dr Anna Barnard – Group Leader

AnnaAnna is a Wellcome Trust Sir Henry Dale Fellow in the Department of Chemistry and the Insitute of Chemical Biology. 

After graduating with an MChem degree from Durham University in 2008, Anna began a PhD in Chemistry with Professor David Smith at the University of York on self-assembling dendrons with applications in gene delivery which included a research visit at the University of Illinois. From 2012, she worked as a post-doctoral research associate with Professor Andy Wilson at the University of Leeds for 2 years on the development of novel inhibitors of protein-protein interactions. She then carried out a post-doc at Imperial College with Professor Ed Tate for before starting a Junior Research Fellowship at Imperial in October 2015. In 2019 she was awarded a prestigious Sir Henry Dale Fellowship by the Wellcome Trust.

Postdoctoral Research Associates

DennisDr Dennis Worm - PDRA May 2019-Present

After graduating with an MSci in Biochemistry from the Ruhr-University Bochum (Germany) in 2014, I started a PhD in Chemistry with Professor Annette Beck-Sickinger at Leipzig University (Germany).
My thesis centred around receptor-targeting peptide-drug conjugates for selective cancer therapy, with a major focus on boron-modified peptides as novel agents for the boron neutron capture therapy.
 
In May 2019, I joined the Barnard Group at Imperial College as post-doctoral research associate to work on the development of novel peptide inhibitors for bacterial persistence.
 
 

Guilherme Dr Guilherme Vieira de Castro - PDRA June 2019-Present

I obtained my BSc and MSc in Chemistry from the Federal University of ABC (São Paulo, Brazil), where I worked with the organic synthesis of nuclear receptor modulators under the supervision of Prof. Mirela Sairre. In 2015 I joined the group of Prof. Alessio Ciulli in the University of Dundee (Scotland, UK) as a PhD student, working with fragment-based ligand discovery applied to E3 ubiquitin ligases.

I joined the Barnard group in 2019 to keep expanding my skills in the interface between chemistry and biology, developing tools to study and inhibit bacterial persistence. 


Postgraduate students

RashiRachelle Kahan (PhD Student 2019-2023)

I graduated Chemistry with Biomedicine (MSci) studying at King’s College London where I developed great interest in using chemical tools to study and target proteins and their interactions. I carried out my final year research project with Dr Manuel Müller involving the synthesis and chemical evaluation of p53 heterotetramers, investigating the effects of post-translational modifications on their functionality.

I started my PhD in 2019 jointly supervised by Dr Anna Barnard and Dr Louise Walport, researching novel cyclic peptide inhibitors for toxin proteins involved in bacterial persistence.

Undergraduate

Undergraduate Students

LucyLucy Haggerty - MSci Student 2019/20

I am a fourth year MSci student studying Chemistry with Medicinal Chemistry at Imperial. I am currently undertaking my final year research project in the Barnard Group, working on the design and synthesis of novel peptide inhibitors to reverse bacterial persistence.

Henry Wilson - MSci Student 2019/20

 

RaquelRaquel Garcia Ferrer

I am an Erasmus Chemistry Student 2019 from Universitat de València taking my masters project in the Barnard group. I am  investigating protein/DNA interactions involved in bacterial persistence. My project is co-supervised by Dr Marco Di Antonio.

OanaOana Popescu - BSc Student 2019

I am a final-year BSc Chemistry Student at Imperial College, currently working on my dissertation with the Barnard Group.  My current project  aims to optimise the synthesis of the Doc protein in E. coli, known to be responsible for inducing bacterial dormancy which leads to persistence.

 

 


Alumni

Postdoctoral Research Associates

Fiona Rowan Jan 2017 - April 2018

PhD Students

Theo Flack 2015-2019

MRes Students

Clara Bernardi 2018/19, Muhammed Haque 2017/18, Yingchao Wang 2016/17, Dan Miles 2016/17, Huda Baldo 2015/16

Undergraduate Project Students (MSci/BSc)

Pete Gobbett (BSc) 2019, Ana Losada de la Lastra (MSci) 2017/18, Hannah Kiely-Collins (MSci) 2017/18, Michelle Tan (MSci) 2015/16

Erasmus/Exchange Students

Oliver Fischer 2017, Femke Meijer 2016/17