Overview
The Integrated Research Application System (IRAS) is where you will submit your formal application for ethical review. This applies to all clinical trials occurring in the UK, that are not assessed by other research ethics committees (such as the Imperial College Research Ethics Committee (ICREC)).
If you are not sure whether you need to submit an IRAS application, check in with your supervisor or your Chief Investigator.
This library collates the most common types of IRAS application, and includes:
- Completed Project Filters for each form type - Check which boxes are ticked to see which form your project would need.
- Blank template forms - Downloadable in PDF format so you can prepare your answers prior to starting an application.
- Example completed forms - Some of the researchers here have been kind enough to share their completed forms with us as examples. If you would like to share a completed (and approved) form with us, get in touch with us here.
As there is a huge number of possible combinations of answers to the project filter questions that define the IRAS form you need to complete, we have only recorded a small number of the most common forms. If your project does not fall under one of the forms recorded here, you can use the IRAS system to generate the one you need by following these instructions:
- Create / login to your IRAS account at https://www.myresearchproject.org.uk/
- Select "My Projects"
- Select "New Project"
- Define a title for your project
- Complete the Project Filter questions that follow. Some questions will change depending on your answers.
- When complete, select "Navigate" at the bottom of the page
- Select "Print blank reference only PDF for the full project dataset". N.B. You must have pop-ups enabled in your browser to begin the download.
- Save
You can download and view the other forms you need from the "Project Forms" sidebar, after clicking the "Navigate" button in the above instructions:

IRAS Library
- 01. Clinical Trial of an Investigational Medicinal Product (CTIMP)
- 02. Clinical Investigation of a Medical Device (commercially/manufacturer funded)
- 02A. Clinical Investigation of a Medical Device (other funding) - No commercialisation intended
- 03. Other clinical trial studying a novel intervention, or RCT comparison
- 04. Study limited to human tissue samples and data (identifiable)
- 05. Study limited to working with human tissue and data (non-identifiable)
- 06. Study using questionnaires or interviews (qualitative or mixed methods)
- 07. Study involving qualitative methods only
- 08. Basic science study of human participants (imaging and/or physical exam)
- 09. Basic Science study of human participants (physical exam and new samples)
- 10. Basic science study of human participants (new and existing samples)
CTIMP projects are now submitted via the new IRAS system. You can find out more, including how to access the new system, here.

Download the template form here: Clinical Trial of an Investigational Medicinal Product - IRAS Template (PDF)
_Project-Filter.png)
Download the template form here: Clinical Investigation of a Medical Product (commercially funded) (PDF)

Download the blank template form here: Clinical Investigation of a Medical Product (other funding, no commercial) (PDF)
Download a completed example form here: Completed example IRAS 2A (PDF)

Download the blank template form here: Other clinical trial or RCT for a novel intervention - Blank template (PDF)

Download the blank template of this form here: Study limited to human tissue and data (identifiable) (PDF)

Download the blank template form here: Study limited to human tissue and data (non-identifiable) (PDF)

Download the blank template form here: Study administering questionnaires (qualitative or mixed methods) (PDF)
Download an example of a completed form here: Study administering questionnaires - Completed example (PDF)

Download the blank template form here: Study involving qualitative methods only (PDF)

Download the blank template form here: Basic science study of human participants (imaging and/or physical exam) (PDF)

Download the blank template form here: Basic science study of human participants (physical exam and new samples) (PDF)
Download a completed example here: Basic science study - Completed example (PDF)

Download the blank template form here: Basic science study of human participants (new and existing samples) (PDF)
Download a completed example form here: Basic science study (new and existing samples) - Completed example (PDF)
