Publications from Pharmacat projects:

1. "Clarification of the role of water in proline-mediated aldol reactions", N. Zotova, A. Franzke, A. Armstrong and D.G. Blackmond, J. Am. Chem. Soc., 2007, 129, 15100. DOI: 10.1021/ja0738881

2. "Kinetic and Mechanistic Studies of Proline-Mediated Direct Intermolecular Aldol Reactions", N. Zotova, L. J. Broadbelt, A. Armstrong, and D.G. Blackmond, Bioorg. Med. Chem. Lett., 2009, 19, 3934. DOI: 10.1016/j.bmcl.2009.03.112

3. "A Coherent Mechanistic Rationale for Additive Effects and Autoinductive Behavior in Proline-Mediated Reactions", N. Zotova, A. Moran, A. Armstrong, and D. G. Blackmond, Adv. Synth. Catal. 2009, 351, 2765. DOI: 10.1002/adsc.200900665

4. “Catalysis in Flow: Practical and Selective Aerobic Oxidation of Alcohols”, N. Zotova, K. Hellgardt, G. H. Kelsall, A. S. Jessiman and K. K. Hii, Green Chem., 2010, 12, 2157-2163. DOI: 10.1039/c0gc00493f

5. “Catalysis in Flow: Au-Catalysed Alkylation of Amines by Alcohols”, N. Zotova, F. J. Roberts, G. H. Kelsall, A. S. Jessiman, K. Hellgardt, and K. K. Hii, Green Chem., 2012, 14, 226. DOI:10.1039/c1gc16118k

6. “Speciation of Pd(OAc)₂ in Ligandless Suzuki-Miyaura Reactions”, L. A. Adrio, B. N. Nguyen, G. Guilera, A. G. Livingston and K. K. Hii, Cat. Sci. Tech., 2012, 2, 316. DOI: 10.1039/c1cy00241d

7. "Catalysis in flow: Operando study of Pd catalyst speciation and leaching", J. B. Brazier, B. N. Nguyen, L. A. Adrio, E. M. Barreiro, W. P. Leong, M. A. Newton, S. J. A. Figueroa, K. Hellgardt and K. K. Hii, Catalysis Today, 2014, 229, 95. DOI: 10.1016/j.cattod.2013.10.079.

8. "Fabrication of hybrid polymer/metal organic framework membranes: mixed matrix membranesversus in situ growth", J. Campbell, G. Szekely, R. P. Davies, D. C. Braddock and A. G. Livingston, J. Mater. Chem. A, 2014, 2, 9260-9271. DOI: 10.1039/C4TA00628C

9. "Controlling Crystallization via Organic Solvent Nanofiltration: The Influence of Flux on Griseofulvin Crystallization", J. Campbell, L. G. Peeva and A. G. Livingston, Cryst. Growth Des., 2014, 14, 192–2200. DOI: 10.1021/cg401708s

10. "Metal-Free Hydrogenation Catalyzed by an Air-Stable Borane: Use of Solvent as a Frustrated Lewis Base", D. J. Scott, M. J. Fuchter and A. E. Ashley, Angew. Chem. Int. Ed. 2014, 53, 10218-10222. DOI: 10.1002/anie.201405531

11. "Nonmetal Catalyzed Hydrogenation of Cabonyl Compounds", D. J. Scott, M. J. Fuchter and A. E. Ashley, J. Am. Chem. Soc., 2014, 136, 15813–15816. DOI: 10.1021/ja5088979

12. "Chemo- and Diasteroselectivities in the Electrochemical Reduction of Maleimides", K. Rix, G. H. Kelsall, K. Hellgardt and K. K. Hii, ChemSusChem, 2015, 8, 665 – 671, DOI: 10.1002/cssc.201403184

13. "Synthesis, Characterisation and Reactivity of Copper(I) Amide Complexes and Studies on their Role in the Modified Ullmann Amination Reaction", S. Sung, D. C. Braddock, A. Armstrong, C. Brennan, D. Sale, A. J. P. White, and R. P. Davies, Chem. Eur. J., 2015, 21, 7179-7192. DOI: 10.1002/chem.201405699

14. “Operando XAFS of supported Pd nanoparticles in flowing ethanol/water mixtures: implications for greener catalysis”, M. A. Newton, J. B. Brazier, E. M. Barreiro, C. J. Mulligan, S. Parry, H. Emmerich, L. A. Adrio, K. Hellgardt and K. K. Hii, Green Chem. 2016, 18, 406-411. DOI: 10.1039/c5gc01600b.

15. “Electronic structures of cyclometalated palladium complexes in the higher oxidation states”, B. N. Nguyen, L. A. Adrio, T. Albrecht, A. J. P. White, M. A. Newton, M. Nachtegaal, S. J. A. Figueroa, and K. K. Hii, Dalton Trans., 2015, 44, 16586 – 16591. DOI: 10.1039/c5dt02104a

16. “Facile Protocol for Water-Tolerant "Frustrated Lewis Pair"-Catalyzed Hydrogenation”, D. J. Scott, T. R. Simmons, E. J. Lawreance, G. G. Wildgoose, M. J. Fuchter and A. E. Ashley, ACS Catal., 2015, 5, 5540-5544. DOI: 10.1021/acscatal.5b01417

17. "Improving the permeance of hybrid polymer/metal–organic framework (MOF) membranes for organic solvent nanofiltration (OSN) – development of MOF thin films via interfacial synthesis", J. Campbell, R. P. Davies, D. C. Braddock and A. G. Livingston, J. Mater. Chem. A 2015, 3, 9668-9674. DOI: 10.1039/C5TA01315A

18. "Hybrid polymer/MOF membranes for Organic Solvent Nanofiltration (OSN): Chemical modification and the quest for perfection", J. Campbell, J. Da Silvao Burgal, G. Szekely, R. P. Davies, D. C. Braddock, A. G. Livingston, J. Mem. Sci. 2016, 503, 166–176. DOI: 10.1016/j.memsci.2016.01.024

19. "Mechanistic Studies on the Copper-Catalyzed N‐Arylation of Alkylamines Promoted by Organic Soluble Ionic Bases", S. Sung, D. Sale, D. C. Braddock, A. Armstrong, C. Brennan, R. P. Davies, ACS Catal. 2016, 6, 3965–3974. DOI: 10.1021/acscatal.6b00504

20. "Versatile Catalytic Hydrogenation Using A Simple Tin(IV) Lewis Acid", D. J. Scott, N. A. Phillips, J. S. Sapsford, A. C. Deacy, M. J. Fuchter, A. E. Ashley, Angew. Chem. Int. Ed. 2016, 55, 14738-14742. DOI: 10.1002/anie.201606639

21. "An assessment of solvent effects on the selectivity of an alkylation reaction: A comparison between experiments and computations", A. Diamanti, E. Grant, Z. Ganase, A. M. Rea, A. Galindo, C. S. Adjiman, AIChE Annual Meeting, 2016.

22. “Mechanistic and Performance Studies on the Ligand-Promoted Ullmann Amination Reaction”, Q. A. Lo, D. Sale, D. C. Braddock, R. P. Davies, ACS Catal. 2018, 8, 101-109. DOI: 10.1021/acscatal.7b03664.

23. “Tetramethyl Orthosilicate (TMOS) as a Reagent for Direct Amidation of Carboxylic Acids” D. C. Braddock, P. D. Lickiss, B. C. Rowley, D. Pugh, T. Teresa Purnomo, G. Santhakumar, S. J. Fussell, Org. Lett. 2018, 20, 950-953. DOI: 10.1021/acs.orglett.7b02492. 

24. "Direct Reductive Amination of Carbonyl Compounds Catalyzed by a Moisture Tolerant Tin(IV) Lewis Acid", J. S. Sapsford, D. J. Scott, N. J. Allcock, M. J. Fuchter, C. J. Tighe, A. E. Ashley, Adv. Synth. Catal., 2018, 360, 1166-1071. DOI: 10.1002/adsc.201701418

25. "Base-free, tunable, Au-catalyzed oxidative esterification of alcohols in continuous flow", F. J. Roberts, C. Richard, F. W. Zemichael, K. K. Hii, K. Hellgardt, C. Brennan, D. A. Sale, React. Chem. Eng. 2018, 3, 942-948. DOI: 10.1039/c8re00085a.

26. "New Insights into the Reaction Capabilities of Ionic Organic Bases in Cu‐Catalyzed Amination", Q. A. Lo, D. Sale, D. C. Braddock and R. P. Davies, Eur. J. Org. Chem. 2019, 1944-1951. DOI: 10.1002/ejoc.201900109

27. "Diazo-Transfer Reagent 2-Azido-4,6-dimethoxy-1,3,5-triazine Displays Highly Exothermic Decomposition Comparable to Tosyl Azide", S. P. Green, A. D. Payne, K. M. Wheelhouse, J. P. Hallett, P. W. Miller and J. A. Bull,  J. Org. Chem. 2019, 84, 5893-5898. DOI: 10.1021/acs.joc.9b00269

28. "Thermal Stability and Explosive Hazard Assessment of Diazo Compounds and Diazo Transfer Reagents", S. P. Green,  K. M. Wheelhouse, A. D. Payne, J. P. Hallett, P. W. Miller and J. A. Bull, Org. Process Res. Dev. 2020, 24, 67–84. DOI: 10.1021/acs.oprd.9b00422.

29. "On the Use of Differential Scanning Calorimetry for Thermal Hazard Assessment of New Chemistry: Avoiding Explosive Mistakes",  S.P. Green, K. M. Wheelhouse, A. D. Payne, J. P. Hallett, P. W. Miller, J. A. Bull, J. A. Angew. Chem. Int. Ed. 2020, DOI: 10.1002/anie.202007028.

30. “On the Use of Triarylsilanols as Catalysts for Direct Amidation of Carboxylic Acids” D. C. Braddock, B. C. Rowley, P. D. Lickiss, S. J. Fussell, R. Qamar, D. Pugh, H. S. Rzepa and A. J. P. White J. Org. Chem. 2023, 88, 9853–9869. DOI: 10.1021/acs.joc.3c00585.

31. “Homeopathic Palladium Catalysis? The observation of distinct kinetic regimes in a ‘ligandless’ Heck reaction at (ultra-)low catalyst loadings”, O. J. Newton, J. Richardson, K. Hellgardt, K. K. Hii, J. Catal. 2023, 424, 29-38. DOI: 10.1016/j.jcat.2023.05.005.