Mood Instability Research


Our research focuses on mood instability: rapid changes in affect that are difficult to regulate. Mood instability is a common feature across mental disorders and one of the first manifestations of distress in young people. Individuals who experience mood instability find current therapies, both pharmacological and psychological, less beneficial than the rest of the population.


Experimental Studies

We aim to understand the cognitive mechanisms that drive mood instability and associated behaviours, such as self-harm, using a variety of methods including behavioural experiments, neuroimaging, physiological measurements, cognitive and pharmacological manipulation to identify targets for new treatments.

In particular we are interested in episodic future simulation; the process of imagining future scenarios that we commonly use to regulate emotions, plan and help us make decisions.

Ongoing studies:

VISIONS OF THE FUTURE IN THE BRIAN: understanding cognitive biases in episodic future simulation in Bipolar Spectrum Disorders: a functional neuroimaging study (NRES ref: 15/EE/0199) - this study has now completed recruitment.

How does simulating vivid emotional future scenarios impact on mood?

IMAGINE Project: Investigating Motivational Abnormalities Guiding self-harm in young peoplethis project aims to understand how reward processing contributes to young people's motivation to self-harm, and how it might maintain the behaviour.

Imaginator logo

Treatment Development Studies

Treatment Development Studies

We aim to translate our experimental findings into the development of brief interventions and digital tools that can support young people with mood instability. 

Ongoing studies:

Can we use adaptive future simulation to target self-harm behaviour?

You can find the  IMAGINATOR trial protocol here, and more information on how we developed the IMAGINATOR app here. Funded by: East of England Collaboration for Leadership in Applied Heath Research & Care (CLAHRC). This study has now completed recruitment.

Digital Mental Health


Across our areas of research we are interested in how digital tools impact on young people’s mental health, and how they can be used to promote emotional well-being.

We are collaborating with researchers from the School of Public Health to investigate the mechanisms by which wireless devices can affect the mental health of adolescents, so if you’d like to take part this is the link (SCAMP study)

Research team