Biomimetic Dentine

Benjamin Miles A number of peptides and proteins have been shown to be active agents in biomineralization of natural structures like teeth, whilst simultaneously the high throughput screening of peptides by biopanning and phage display has given rise to a class of peptide known as genetically engineered peptides for inorganics (GEPI). GEPIs have been shown to perform a number of in vitro applications for nanoscale device fabrication namely the promotion of growth of inorganic crystal phases  and highly specific non-covalent immobilisation. I work to combine the functionality of proteins with the specific tethering properties of GEPIs by the development of fusion proteins to give rise to self assembled protein layers on inorganic surfaces like semiconductor materials, via biomimetic biomineralization processes.

Mini Bio:

  • In 2011 I achieved a MRes degree in Chemical Biology of Health and Disease at the grade of distinction from the Institute of Chemical Biology (ICB), Imperial College London. My interests include the integration between biology and the solid-state and the use of biology in the micro and nano fabrication of devices. Such devices include diagnostic tools and single molecule detectors like nanopores. 
  • Ben attended the University of Leeds between 2007 and 2010 where he was awarded a 2.i (Hons) BSc degree in Nanotechnology by the Centre of Molecular Nano Science (CMNS). Whilst conducting his undergraduate degree he was awarded a Nuffield undergraduate research bursary to conduct research in biosensor fabrication.

You can follow my work at www.benmil.es and on twitter atwww.twitter.com/BennMiles and additionally my other group at www.twitter.com/CassGroup

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Contact

Professor Joshua B. Edel
Department of Chemistry
South Kensington Campus
SW7 2AZ London

Tel: +44 (0)20 7594 0754
Email: joshua.edel@imperial.ac.uk

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