Drug resistance is a major challenge for cancer therapy, often due to differences that arise within cancer cells within and between tumours. 2D cells are frequently used to study how cancer cells behave in response to drugs, unfortunately they do not provide an accurate representation of how cancer cells behave inside the human body in a 3D context. 3D cell models have been developed that more accurately mimic the tumour environment. However, it is difficult to image and study 3D cells using conventional microscopes, the MACH3CANCER Accelerator project is building the technology required to image these 3D cells. This will provide more information of how cancer cells become resistant to drugs, as well as aid us in discovering new, more effective drugs.
Our speakers include researchers and our patient advocates.
Programme:
- Clinical challenges of drug resistance – Iain McNeish (Imperial College London)
- Drug resistance: Outliers in response to therapy- Erik Sahai (Francis Crick Institute)
- Utilising 3D cell cultures in drug discovery research – Neil Carragher (University of Edinburgh)
- Oblique plane microscopy (OPM): Rapid imaging of 3D cell cultures – Chris Dunsby (Imperial College London)
- Patient perspective – MACH3CANCER Patient Advocates
- Questions from the audience
Please visit the www.mach3cancer.org website to learn more about MACH3CANCER Accelerator project or contact Aline Kimonyo (a.kimonyo@imperial.ac.uk) for more details regarding this event.
Keep up-to-date with our research by following us on Twitter @MACH3CANCERMACH3CANCER is funded by CRUK and the AECC.