Leveraging machine learning powered imaging analysis and large-scale genomics for drug discovery
Recent advances in global biobanking efforts have offered medical researchers access to a wealth of genome and imaging data.
In this lecture, Professor Declan O’Regan from Imperial and Dr Daniel Freitag from Bayer will explain how they have worked together to harness this as part of the UK Biobank study.
The project brings together two key scientific disciplines: 1) application state-of-the-art machine learning methods to MRI imaging data, and 2) large-scale human genomic analyses. In combining these two disciplines the joint collaboration was able to extract key insights from those data, which are relevant for drug discovery and clinical translation in the cardiovascular and heart failure area.
About the speakers
Professor Declan O’Regan is an MRC Investigator and Professor of Imaging leading the Computational Cardiac Imaging Group at the London Institute of Medical Sciences. He is also Director for Imaging Research at Imperial College Healthcare NHS Trust. His work is focussed on using machine learning to analyse cardiac imaging to understand the genetic and environmental causes of heart disease.
Dr Daniel Freitag is head of the Biomedical Data Science team within Research & Early Development – Precision Medicine at Bayer AG, Division Pharmaceuticals in Wuppertal, Germany. With his team, he is responsible for enabling data-driven decision making based on large-scale human -omics data across the Bayer Pharma portfolio for non-Oncology indications. He has a strong research interest in human genetics and other large scale “-omics” disciplines, drug discovery & development and digital health, with the overall ambition of making a difference to patients.
Chair: Professor Martin Wilkins is Professor of Clinical Pharmacology at Imperial College London. He is Vice Dean (Research) for the Faculty of Medicine, a role he combines with Director of the British Heart Foundation Imperial College Centre of Research Excellence and Director of the National Institute of Health Research Imperial College Clinical Research Facility at Hammersmith Hospital.
Joining the event
This will be a live event, please register through the link provided.
We warmly welcome staff and students from across Imperial who would like to learn about how translational research and academic-industry collaboration is helping create a new generation of medical treatments.
In Person
South Kensington Campus – Huxley Building, Lecture Theatre 311