We are delighted to welcome Professor Sarah McClelland from the Barts Cancer Institute, Queen Mary University of London as our guest speaker for the upcoming Division of Cancer Seminar. Professor McClelland is an internationally recognised cancer biologist whose research focuses on understanding the molecular mechanisms that drive chromosomal instability in cancer.
Professor McClelland leads a research programme investigating how abnormalities in chromosome number and structure arise in tumour cells and contribute to cancer evolution, drug resistance and poor patient outcomes. Her laboratory studies chromosomal instability across several cancer types, including ovarian, pancreatic, prostate and colorectal cancers, with the ultimate aim of identifying new therapeutic vulnerabilities and improving treatment strategies for patients.
Since establishing her laboratory at the Barts Cancer Institute in 2013, Professor McClelland has made significant contributions to our understanding of genome instability and chromosome segregation in cancer. Her work has been published in leading journals including Nature, Cancer Research, Genome Biology, EMBO Journal and Cell Reports, and is supported by major funding from organisations including Cancer Research UK the Medical Research Council and the Biotechnology and Biological Sciences Research Council.
We look forward to welcoming Professor McClelland and hearing about her latest research into the origins, consequences and therapeutic opportunities associated with chromosomal instability in cancer.