In this section
@article{Eng:2023:10.1016/j.jhepr.2023.100835,
author = {Eng, P and Forlano, R and Tan, T and Manousou, P and Dhillo, W and Izzi-Engbeaya, C},
doi = {10.1016/j.jhepr.2023.100835},
journal = {JHEP Reports},
title = {Non-alcoholic fatty liver disease in women – current knowledge and emerging concepts},
url = {http://dx.doi.org/10.1016/j.jhepr.2023.100835},
volume = {5},
year = {2023}
}
TY - JOUR
AB - Non-alcoholic fatty liver disease (NAFLD) is a major cause of liver disease worldwide, affecting up to 30% of adults. Progression to non-alcoholic steatohepatitis (NASH) is a key risk factor for cirrhosis, hepatocellular carcinoma and cardiovascular events. Alterations in reproductive hormones are linked to the development and/or progression of NAFLD/NASH in women. Women with Polycystic Ovary Syndrome (PCOS) and those with estrogen deficiency are at increased risk of NAFLD/NASH, with higher mortality rates in older women compared to men of similar ages. NAFLD/NASH is currently the leading indication for liver transplantation in women without hepatocellular carcinoma. Therefore, a better understanding of NAFLD in women is needed to improve outcomes. In this review, we discuss the hormonal and non-hormonal factors contributing to NAFLD development and progression in women. Furthermore, we highlight areas of focus for clinical practice and for future research.
AU - Eng,P
AU - Forlano,R
AU - Tan,T
AU - Manousou,P
AU - Dhillo,W
AU - Izzi-Engbeaya,C
DO - 10.1016/j.jhepr.2023.100835
PY - 2023///
SN - 2589-5559
TI - Non-alcoholic fatty liver disease in women – current knowledge and emerging concepts
T2 - JHEP Reports
UR - http://dx.doi.org/10.1016/j.jhepr.2023.100835
UR - https://www.sciencedirect.com/science/article/pii/S2589555923001660
VL - 5
ER -