BibTex format
@article{Brent:2018:10.3201/eid2403.170785,
author = {Brent, AJ and Nyundo, C and Langat, J and Mulunda, C and Wambua, J and Bauni, E and Sande, J and Park, K and Williams, TN and Newton, CRJ and Levin, M and Scott, JAG},
doi = {10.3201/eid2403.170785},
journal = {Emerging Infectious Diseases},
pages = {514--523},
title = {Prospective observational study of incidence and preventable burden of childhood tuberculosis, Kenya},
url = {http://dx.doi.org/10.3201/eid2403.170785},
volume = {24},
year = {2018}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Substantial progress has been made in the fight against tuberculosis (TB); however, new approaches are needed to achieve the current target set by the World Health Organization (WHO) to reduce TB incidence to 90% of 2016 levels by 2035 (1). A key element of WHO’s End TB Strategy is the prioritization of preventive treatment (2). However, the preventable burden of childhood TB has not been quantified in prospective epidemiologic studies, and globally, only an estimated 7% of eligible children received isoniazid chemoprophylaxis in 2015 (1).Diagnosis of TB is more challenging in children than in adults (3). In low-resource settings, where TB burden is highest, diagnosis often relies on poorly validated clinical algorithms (4). As a result, adequate surveillance data are lacking, and published estimates of the global childhood TB burden vary widely (1,5–11). High-quality prospective data on the TB burden and case detection rate (CDR) in children are recognized priorities (8,11,12), and population-level data showing the preventable burden of childhood TB might reinforce the public health case for chemoprophylaxis in children. We designed the Kilifi Improving Diagnosis and Surveillance of Childhood TB (KIDS TB) Study to estimate the incidence, CDR, risk factors, and preventable burden of childhood TB in Kenya.
AU - Brent,AJ
AU - Nyundo,C
AU - Langat,J
AU - Mulunda,C
AU - Wambua,J
AU - Bauni,E
AU - Sande,J
AU - Park,K
AU - Williams,TN
AU - Newton,CRJ
AU - Levin,M
AU - Scott,JAG
DO - 10.3201/eid2403.170785
EP - 523
PY - 2018///
SN - 1080-6040
SP - 514
TI - Prospective observational study of incidence and preventable burden of childhood tuberculosis, Kenya
T2 - Emerging Infectious Diseases
UR - http://dx.doi.org/10.3201/eid2403.170785
UR - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000425371700014&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
VL - 24
ER -