Imperial publications

Search or filter publications

Search publications Search

Filter by type:

Filter by publication type

• Book
• Book chapter
• Conference paper
• Journal article
• Other
• Patent
• Poster
• Report
• Scholarly edition
• Software
• Thesis dissertation
• Working paper

Filter by year:

Filter from 202620252024202320222021202020192018201720162015201420132012201120102009200820072006200520042003200220012000199919981997199619951994199319921991199019891988198719861985198419831982198119801979197819771976197519741973 to Filter to 202620252024202320222021202020192018201720162015201420132012201120102009200820072006200520042003200220012000199919981997199619951994199319921991199019891988198719861985198419831982198119801979197819771976197519741973

---

Search results

• Journal article
  Arshad H, Lack G, Durham SR, Penagos M, Larenas-Linneman D, Halken Set al., 2024,

  Prevention Is Better than Cure: Impact of Allergen Immunotherapy on the Progression of Airway Disease

  , JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, Vol: 12, Pages: 45-56, ISSN: 2213-2198
  • Cite
• Journal article
  Goldsmith LP, Roberts A, Flohr C, Boyle RJ, Ussher M, Perkin MRet al., 2024,

  Routine infant skincare advice in the UK: A cross-sectional survey

  , CLINICAL AND EXPERIMENTAL ALLERGY, Vol: 54, Pages: 56-60, ISSN: 0954-7894
  • Cite
• Journal article
  Murray SM, Pose E, Wittner M, Londono M-C, Schaub G, Cook J, Dimitriadis S, Meacham G, Irwin S, Lim Z, Duengelhoef P, Sterneck M, Lohse AW, Perez V, Trivedi P, Bhandal K, Mullish BH, Manousou P, Provine NM, Avitabile E, Carroll M, Tipton T, Healy S, Burra P, Klenerman P, Dunachie S, Kronsteiner B, Maciola AK, Pasqual G, Hernandez-Gea V, Garcia-Pagan JC, Lampertico P, Iavarone M, Gines P, Luetgehetmann M, zur Wiesch JS, Russo FP, Barnes E, Marjot Tet al., 2024,

  Immune responses and clinical outcomes after COVID-19 vaccination in patients with liver disease and liver transplant recipients

  , JOURNAL OF HEPATOLOGY, Vol: 80, ISSN: 0168-8278
  • Cite
• Journal article
  Vukmirovic M, Benam KH, Rose JJ, Turner S, Magin CM, Lagares D, Cohen AH, Kaminski N, Hirota JA, Maher TM, Konigshoff M, Mallampalli RK, Sheppard D, Tarran R, Gomer RH, Kenyon NJ, Morris D, Hobbie S, Raju SV, Petrache I, Watkins T, Kumar R, Lam WA, Sherer T, Hecker Let al., 2024,

  Challenges and Opportunities for Commercializing Technologies in the Pulmonary Arena An Official American Thoracic Society Report

  , ANNALS OF THE AMERICAN THORACIC SOCIETY, Vol: 21, Pages: 1-11, ISSN: 1546-3222
  • Cite
• Journal article
  Di Pilato V, Codda G, Niccolai C, Willison E, Wong JLC, Coppo E, Frankel G, Marchese A, Rossolini GMet al., 2024,

  Functional features of KPC-109, a novel 270-loop KPC-3 mutant mediating resistance to avibactam-based ,B-lactamase inhibitor combinations and cefiderocol

  , INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, Vol: 63, ISSN: 0924-8579
  • Cite
• Journal article
  Taouli B, Ba-Ssalamah A, Chapiro J, Chhatwal J, Fowler K, Kang TW, Knobloch G, Koh D-M, Kudo M, Lee JM, Murakami T, Pinato DJ, Ringe KI, Song B, Tabrizian P, Wang J, Yoon JH, Zeng M, Zhou J, Vilgrain Vet al., 2024,

  Consensus report from the 10th global forum for liver magnetic resonance imaging: multidisciplinary team discussion (may, 10.1007/s00330-023-09919-z, 2023)

  , EUROPEAN RADIOLOGY, Vol: 34, Pages: 724-725, ISSN: 0938-7994
  • Cite
• Journal article
  Agirrezabal I, Bouattour M, Pinato DJ, D'Alessio A, Brennan VK, Carion PL, Shergill S, Amoury N, Vilgrain Vet al., 2024,

  Efficacy of transarterial radioembolization using Y-90 resin microspheres versus atezolizumab-bevacizumab in unresectable hepatocellular carcinoma: A matching-adjusted indirect comparison

  , EUROPEAN JOURNAL OF CANCER, Vol: 196, ISSN: 0959-8049
  • Cite
• Journal article
  Stefani S, Buti N, Hart ACJ, Paul D, Rizvi N, Ragoonanan V, Vladescu C, Szydlo R, Ademokun C, Jansen AJG, Cooper Net al., 2024,

  Safety and efficacy of SARS-CoV-2 vaccination in patients with immune thrombocytopenia: A two-centre review

  , BRITISH JOURNAL OF HAEMATOLOGY, Vol: 204, Pages: 324-328, ISSN: 0007-1048
  • Cite
• Journal article
  Cooper N, Ghanima W, Vianelli N, Valcarcel D, Yavasoglu I, Melikyan A, Ruiz EY, Haenig J, Somenzi O, Lee J, Clark J, Zhang Y, Zaja Fet al., 2024,

  Sustained response off-treatment in eltrombopag-treated adult patients with ITP who are refractory or relapsed after first-line steroids: Primary, final, and ad-hoc analyses of the Phase II TAPER trial

  , AMERICAN JOURNAL OF HEMATOLOGY, Vol: 99, Pages: 57-67, ISSN: 0361-8609
  • Cite
  • Citations: 11
• Journal article
  Amaral EP, Namasivayam S, Queiroz ATL, Fukutani E, Hilligan KL, Aberman K, Fisher L, Bomfim CCB, Kauffman K, Buchanan J, Santuo L, Gazzinelli-Guimaraes PH, Costa DL, Teixeira MA, Barreto-Duarte B, Rocha CG, Santana MF, Cordeiro-Santos M, Barber DL, Wilkinson RJ, Kramnik I, Igarashi K, Scriba T, Mayer-Barber KD, Andrade BB, Sher Aet al., 2024,

  BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility

  , Nature Microbiology, Vol: 9, Pages: 120-135, ISSN: 2058-5276

  Oxidative stress triggers ferroptosis, a form of cellular necrosis characterized by iron-dependent lipid peroxidation, and has been implicated in Mycobacterium tuberculosis (Mtb) pathogenesis. We investigated whether Bach1, a transcription factor that represses multiple antioxidant genes, regulates host resistance to Mtb. We found that BACH1 expression is associated clinically with active pulmonary tuberculosis. Bach1 deletion in Mtb-infected mice increased glutathione levels and Gpx4 expression that inhibit lipid peroxidation. Bach1-/- macrophages exhibited increased resistance to Mtb-induced cell death, while Mtb-infected Bach1-deficient mice displayed reduced bacterial loads, pulmonary necrosis and lipid peroxidation concurrent with increased survival. Single-cell RNA-seq analysis of lungs from Mtb-infected Bach1-/- mice revealed an enrichment of genes associated with ferroptosis suppression. Bach1 depletion in Mtb-infected B6.Sst1S mice that display human-like necrotic lung pathology also markedly reduced necrosis and increased host resistance. These findings identify Bach1 as a key regulator of cellular and tissue necrosis and host resistance in Mtb infection.

  • Abstract
  • Publisher Web Link
  • Author Web Link
  • Cite

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.