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Journal articleJohannson KA, Strambu I, Ravaglia C, et al., 2017,
Antacid therapy in idiopathic pulmonary fibrosis: more questions than answers?
, LANCET RESPIRATORY MEDICINE, Vol: 5, Pages: 591-598, ISSN: 2213-2600- Author Web Link
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- Citations: 73
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Journal articleTaslimi Y, Sadeghipour P, Habibzadeh S, et al., 2017,
A novel non-invasive diagnostic sampling technique for cutaneous leishmaniasis
, PLoS Neglected Tropical Diseases, Vol: 11, ISSN: 1935-2727Accurate diagnosis of cutaneous leishmaniasis (CL) is important for chemotherapy and epidemiological studies. Common approaches for Leishmania detection involve the invasive collection of specimens for direct identification of amastigotes by microscopy and the culturing of promastigotes from infected tissues. Although these techniques are highly specific, they require highly skilled health workers and have the inherent risks of all invasive procedures, such as pain and risk of bacterial and fungal super-infection. Therefore, it is essential to reduce discomfort, potential infection and scarring caused by invasive diagnostic approaches especially for children. In this report, we present a novel non-invasive method, that is painless, rapid and user-friendly, using sequential tape strips for sampling and isolation of DNA from the surface of active and healed skin lesions of CL patients. A total of 119 patients suspected of suffering from cutaneous leishmaniasis with different clinical manifestations were recruited and samples were collected both from their lesions and from uninfected areas. In addition, 15 fungal-infected lesions and 54 areas of healthy skin were examined. The duration of sampling is short (less than one minute) and species identification by PCR is highly specific and sensitive. The sequential tape stripping sampling method is a sensitive, non-invasive and cost-effective alternative to traditional diagnostic assays and it is suitable for field studies as well as for use in health care centers.
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Journal articleTajebe F, Getahun M, Adem E, et al., 2017,
Disease severity in patients with visceral leishmaniasis is not altered by co-infection with intestinal parasites
, PLoS Neglected Tropical Diseases, Vol: 11, ISSN: 1935-2727Visceral leishmaniasis (VL) is a neglected tropical disease that affects the poorest communities and can cause substantial morbidity and mortality. Visceral leishmaniasis is characterized by the presence of Leishmania parasites in the spleen, liver and bone marrow, hepatosplenomegaly, pancytopenia, prolonged fever, systemic inflammation and low body mass index (BMI). The factors impacting on the severity of VL are poorly characterized. Here we performed a cross-sectional study to assess whether co-infection of VL patients with intestinal parasites influences disease severity, assessed with clinical and haematological data, inflammation, cytokine profiles and BMI. Data from VL patients was similar to VL patients co-infected with intestinal parasites, suggesting that co-infection of VL patients with intestinal parasites does not alter disease severity.
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Conference paperIslam R, Abbara A, Clarke S, et al., 2017,
Ovarian volume as a surrogate marker of ovarian recovery following ovarian stimulation with different triggers of oocyte maturation: kisspeptin, GnRH agonist and human chorionic gonadotropin
, 33rd Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology (ESHRE), Publisher: OXFORD UNIV PRESS, Pages: 457-457, ISSN: 0268-1161 -
Conference paperKhoder A, Palanicawandar R, Atta M, et al., 2017,
The choice between stem cell mobilisation with GCSF alone or with GCSF plus chemotherapy may impact on the stem cell transplant service
, 43rd Annual Meeting of the European-Society-for-Blood-and-Marrow-Transplantation (EBMT), Publisher: NATURE PUBLISHING GROUP, Pages: S146-S147, ISSN: 0268-3369 -
Conference paperMonsalvo S, Gabriel I, Sevillano B, et al., 2017,
Exacerbation of multiple sclerosis symptoms in patients undergoing autologous stem cell transplantation
, 43rd Annual Meeting of the European-Society-for-Blood-and-Marrow-Transplantation (EBMT), Publisher: NATURE PUBLISHING GROUP, Pages: S419-S420, ISSN: 0268-3369 -
Conference paperAuner H, Iacobelli S, Bianchi G, et al., 2017,
The impact of melphalan dosage on outcomes of autologous haematopoietic cell transplantation for multiple myeloma: Results from the EBMT collaboration to collect autologous transplant outcomes in lymphoma and myeloma (CALM) study
, 43rd Annual Meeting of the European-Society-for-Blood-and-Marrow-Transplantation (EBMT), Publisher: SPRINGERNATURE, Pages: S473-S474, ISSN: 0268-3369 -
Conference paperAuner H, 2017,
IMiDs, proteasome-inhibitors and antibodies as part of a transplant-package for multiple myeloma
, 43rd Annual Meeting of the European-Society-for-Blood-and-Marrow-Transplantation (EBMT), Publisher: NATURE PUBLISHING GROUP, Pages: S119-S119, ISSN: 0268-3369 -
Conference paperRhone E, Silber E, Mccormick J, et al., 2017,
Autologous haematopoietic stem cell transplant in multiple sclerosis: Updated results from the Pan-London MS group
, 43rd Annual Meeting of the European-Society-for-Blood-and-Marrow-Transplantation (EBMT), Publisher: NATURE PUBLISHING GROUP, Pages: S482-S483, ISSN: 0268-3369 -
Conference paperRhone E, Silber E, Mccormick J, et al., 2017,
Investigating frequency of EBV reactivation following autologous HSCT in patients with multiple sclerosis
, 43rd Annual Meeting of the European-Society-for-Blood-and-Marrow-Transplantation (EBMT), Publisher: NATURE PUBLISHING GROUP, Pages: S495-S495, ISSN: 0268-3369
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