collage of HPRU2 members

Understanding the underlying causes of AMR and HCAI, identifying the best methods to improve antimicrobial use, their potential impact and their cost-effectiveness

The Unit is a partnership between Imperial College and Public Health England.  It has been funded by NIHR for a further five-year term from 1 April 2020 and builds on an existing critical mass of research conducted between 01 April 2014 - 31 March 2020.

The Unit’s Director is Professor Alison Holmes and its PHE lead is Matt Ellington. Find out more about our people here.

The Unit’s current partners are: 

ICHP logo

warwick logo

CAM updated

About us

The National Institute for Health Research (NIHR) has funded the development of a number of Health Protection Research Units (HPRU) in key priority areas. These research units are collaborations between Universities, Public Health England (PHE) and other partner organisations and aim to provide centres of excellence in multi-disciplinary health protection research.

The NIHR HPRU in Healthcare Associated Infections (HCAI) and Antimicrobial Resistance (AMR) at Imperial College London, started on 1 April 2014 and has now renewed five-year funding from 1 April 2020. 

Our HPRU recognises the different skills required to address the threat of AMR and HCAIs, and it brings together researchers from a range of disciplines and professions (including doctors, engineers, epidemiologists, microbiolosts, pharmacists, behavioural scientists, economists, and nurses). Our approach to addressing HCAIs and AMR is via four complementary themes:

  1. Priority pathogens
  2. Precision prescribing
  3. Practice, design and engineering
  4. Population health and policy