In this section
@article{Joos:1995:10.1016/0925-4773(94)00335-k,
author = {Joos, TO and Whittaker, CA and Meng, F and DeSimone, DW and Gnau, V and Hausen, P},
doi = {10.1016/0925-4773(94)00335-k},
journal = {Mech Dev},
pages = {187--199},
title = {Integrin alpha 5 during early development of Xenopus laevis.},
url = {http://dx.doi.org/10.1016/0925-4773(94)00335-k},
volume = {50},
year = {1995}
}
TY - JOUR
AB - The full length sequence of the Xenopus integrin alpha 5 subunit is reported. Analysis of cloned cDNA fragments reveals that alternative polyadenylation of alpha 5 mRNA occurs in the embryo. Furthermore, a variant form of the alpha 5 mRNA is expressed which encodes an integrin alpha 5 subunit with a truncated cytoplasmic domain. Integrin alpha 5 mRNA and protein are expressed in oocytes, eggs and throughout development. Spatial expression of alpha 5 mRNAs is first detected by whole mount in situ hybridization in presumptive neural crest cells and in the somitic mesoderm from the midgastrula stage onwards. In contrast, the alpha 5 protein is present on newly formed plasma membranes beginning at first cleavage. During neurulation, the integrin alpha 5 subunit disappears from the outer layer of the ectoderm, the notochord and the neural tube and accumulates in the sensorial layer of the ectoderm, the somites and the neural crest cells. These results provide evidence for the position specific regulation of alpha subunit expression in early vertebrate embryos.
AU - Joos,TO
AU - Whittaker,CA
AU - Meng,F
AU - DeSimone,DW
AU - Gnau,V
AU - Hausen,P
DO - 10.1016/0925-4773(94)00335-k
EP - 199
PY - 1995///
SN - 0925-4773
SP - 187
TI - Integrin alpha 5 during early development of Xenopus laevis.
T2 - Mech Dev
UR - http://dx.doi.org/10.1016/0925-4773(94)00335-k
UR - https://www.ncbi.nlm.nih.gov/pubmed/7619730
VL - 50
ER -
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