Explore how our undergraduate students apply molecular design principles to real-world challenges in DNA nanotechnology and biomolecular systems.

UG Project 2024/25: Dynamics by Design

We’re pleased to share that our undergraduate project group has successfully completed their 2024/25 project, Dynamics by Design. Their work explores a novel approach to tuning DNA strand displacement reaction rates by introducing base-pair mismatches into toehold regions. Using a modular design and in silico tools like NUPACK, they created a comprehensive database of toehold variants spanning a wide range of kinetics. This work helps overcome modelling limitations and adds a valuable tool to the molecular programming toolkit.

Explore the full project and GitHub repo and don't miss out on the Brochure.

 

  • News
  • Research

Nature Chemistry paper from Rakesh and Javier on enzyme-free DNA templating

Congrats to Rakesh and Javi on our Nature Chemistry paper on enzyme-free DNA dimer templating with weak product inhibition – well done!
  • News
  • Research

UG Project Finished

Our undergraduate team completed their project on a novel tool for kinetic control of DNA reaction systems. Check it out:

  • News
  • Papers

JCP paper from Jeremy on heterogeniety in templated polymer copying

Congratulations to Jeremy, who has published a paper in J. Chem. Phys. on heterogeniety and product detachment in templated polymer copying