In this section
@article{Carhart-Harris:2009,
author = {Carhart-Harris, RL and Nutt, DJ and Munafo, MR and Christmas, DM and Wilson, SJ},
journal = {Psychopharmacology (Berl)},
pages = {187--196},
title = {Equivalent effects of acute tryptophan depletion on REM sleep in ecstasy users and controls},
url = {pm:19585107},
volume = {206},
year = {2009}
}
TY - JOUR
AB - INTRODUCTION: This study sought to test the association between 3,4-methylenedioxymethamphetamine use, serotonergic function and sleep. MATERIALS AND METHODS: Ambulatory polysomnography was used to measure three nights sleep in 12 ecstasy users and 12 controls after screening (no intervention), a tryptophan-free amino acid mixture (acute tryptophan depletion (ATD)) and a tryptophan-supplemented control mixture. RESULTS: ATD significantly decreased rapid eye movement (REM) sleep onset latency, increased the amount of REM sleep and increased the amount of stage 2 sleep in the first 3 h of sleep. There was no difference between ecstasy users' and controls' sleep on the screening night or after ATD. DISCUSSION: These findings imply that the ecstasy users had not suffered significant serotonergic damage as indexed by sleep
AU - Carhart-Harris,RL
AU - Nutt,DJ
AU - Munafo,MR
AU - Christmas,DM
AU - Wilson,SJ
EP - 196
PY - 2009///
SP - 187
TI - Equivalent effects of acute tryptophan depletion on REM sleep in ecstasy users and controls
T2 - Psychopharmacology (Berl)
UR - pm:19585107
VL - 206
ER -
