Citation

BibTex format

@article{Hipolito:2023:nc/niad017,
author = {Hipolito, I and Mago, J and Rosas, FE and Carhart-Harris, R},
doi = {nc/niad017},
journal = {Neuroscience of Consciousness},
title = {Pattern breaking: a complex systems approach to psychedelic medicine},
url = {http://dx.doi.org/10.1093/nc/niad017},
volume = {2023},
year = {2023}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Recent research has demonstrated the potential of psychedelic therapy for mental health care. However, the psychological experience underlying its therapeutic effects remains poorly understood. This paper proposes a framework that suggests psychedelics act as destabilizers, both psychologically and neurophysiologically. Drawing on the ‘entropic brain’ hypothesis and the ‘RElaxed Beliefs Under pSychedelics’ model, this paper focuses on the richness of psychological experience. Through a complex systems theory perspective, we suggest that psychedelics destabilize fixed points or attractors, breaking reinforced patterns of thinking and behaving. Our approach explains how psychedelic-induced increases in brain entropy destabilize neurophysiological set points and lead to new conceptualizations of psychedelic psychotherapy. These insights have important implications for risk mitigation and treatment optimization in psychedelic medicine, both during the peak psychedelic experience and during the subacute period of potential recovery.
AU - Hipolito,I
AU - Mago,J
AU - Rosas,FE
AU - Carhart-Harris,R
DO - nc/niad017
PY - 2023///
SN - 2057-2107
TI - Pattern breaking: a complex systems approach to psychedelic medicine
T2 - Neuroscience of Consciousness
UR - http://dx.doi.org/10.1093/nc/niad017
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:001023755900001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=a2bf6146997ec60c407a63945d4e92bb
UR - https://doi.org/10.1093/nc/niad017
UR - http://hdl.handle.net/10044/1/107101
VL - 2023
ER -

Centre for Psychedelic Research logo