Research Associate in Medicinal Chemistry and Cancer Drug Discovery

We are seeking an outstanding medicinal chemist to lead a collaborative drug discovery project on a novel anticancer drug target, in our group at the Molecular Sciences Research Hub at Imperial’s new White City Campus. You will lead the medicinal chemistry programme and join a team of researchers to apply cutting edge structure-guided drug discovery against a challenging multi-pass transmembrane enzyme upstream of critical signalling pathways in the tumour microenvironment.

For full details and to apply: https://www.imperial.ac.uk/jobs/description/NAT00885/research-associate-medicinal-chemistry-and-cancer-drug-discovery

4 year (1+3) MRes/PhD studentship - Development of novel photochemical probes to investigate quadruplex DNA interactome in living cells

Supervisors: Prof Ramon Vilar Compte, Prof Ed Tate and Dr Marco Di Antonio

This project aims to improve our understanding of the proteins responsible for G4-recongition in cells, which is key to further elucidation of G4s’ biological significance, by developing photoactivatable probes that can label proteins bound to G4s in living cells. For full details see https://www.findaphd.com/phds/project/development-of-novel-photochemical-probes-to-investigate-quadruplex-dna-interactome-in-livings-cells/?p128336. Applications should be made via our chemical biology CDT via our chemical biology CDT: https://www.imperial.ac.uk/chemical-biology/cdt/studentships/projects/

Postdoctoral opportunities

We welcome informal enquiries from potential postdoctoral fellows with outstanding research track records who are prepared to apply for independent research funding, for example from the European Union, HFSP, etc. Full assistance will be given in preparing a competitive research proposal; we have an exceptional track record in accelerating the careers of outstanding postdoctoral researchers, with six Marie Curie fellows in our lab in the past four years. 

PhD studentships 

Any students interested in pursuing postgraduate research in our group should contact me directly; all prospective applicants should have or expect to obtain a 1st class honours degree (or equivalent) in chemistry, biochemistry, or a closely related discipline; non-UK students must be able to obtain independent funding for their studies, e.g. via a government bursary.