Project Title: Investigating the molecular and cellular mechanisms connecting amyloidosis to circadian disruption
Supervisors: Dr Marco Brancaccio, Dr Samuel Barnes
Location: Level 5, Burlington Danes Building, Hammersmith Campus, Du Cane Road, W12 0NN
About Me
I am a PhD student in the Brancaccio laboratory in the Department of Brain Sciences within the UK Dementia Research Institute centre at Imperial College London. My project is focussed on investigating the role of circadian rhythmicity as a form of neurodegeneration suppressor, whose disruption unhinges pathogenic processes thus accelerating the pathogenesis of neurodegenerative diseases such as Alzheimer’s Disease. My unique focus within the lab is using 3D-object based approaches and automation in immunofluorescence image analysis, extracting comprehensive spatial and geometric data from large datasets to enable complex molecular interactions involved in disease pathogenesis to be studied and quantified at greater resolution and efficiency.
Qualifications
2023-2024: MRes Clinical Research: Translational Medicine, Imperial College London
2019-2022: BSc Biomedical Sciences, University of Warwick
Contact Details
Email: j.malcolm23@imperial.ac.uk
LinkedIn: jamie-malcolm-980889218
