Sabino Mendez Pastor
Project title: How do TREM2 gene variants enhance susceptibility to Alzheimer’s disease?
Supervisor: Professor Paul Matthews
Location: Level 7, Sir Michael Uren Hub, White City Campus, 86 Wood Lane, W12 0BZ
About me
After completing my Master’s project at the UK Dementia Research Institute centre at Imperial College London, I decided that the Department of Brain Sciences at Imperial was the perfect place to do a PhD. The centre offers an exceptional opportunity to work and exchange ideas with experts from different areas of dementia research in a supportive environment. I look forward to being inspired by these excellent scientists and collaborating with them to make discoveries that can help people affected by dementia.
Qualifications
- 2022-2023: MRes Experimental Neuroscience (Distinction), Imperial College London
- 2019-2022: BSc Medical Biosciences (First Class Honours), Imperial College London
Outreach
- Great Exhibition Road Festival 2023
Contact details
How temperature and circadian rhythms intersect to regulate a protein shown to protect against neurodegeneration
A new study led by Dr Marco Brancaccio (UK DRI at Imperial) and Dr Marieke Hoekstra (former UK DRI at Imperial, now VIB-KU Leuven Center for Brain & Disease Research) offers a deeper insight into how a neuroprotective pathway is regulated both by temperature and the body clock. This research, published in the journal PNAS, could open up new therapeutic avenues for neurodegenerative disease. Read more on the UK DRI website
Introducing Cynthia Sandor: Pioneering earlier detection of Parkinson’s
Dr Cynthia Sandor, former Emerging Leader at the UK DRI at Cardiff, joins the UK DRI at Imperial as a Group Leader, where she will be tackling early diagnosis of Parkinson’s.
With a background in genetics, Dr Sandor uses computational methods to bring greater understanding to the underlying molecular mechanisms of Parkinson’s. Read more about Cynthia's work on the UK DRI website.
