Work package 3

Overarching theoretical approaches

This project offers a comprehensive investigation of Antimicrobial Stewardship (AS) and Infection Control (IC) behaviours approached as a co-construction of individual, organisational and wider contextual factors. The project examines these factors at the micro-, meso- and macro-levels using theoretical approaches from the fields of strategic management, sociology, psychology, and anthropology. To evaluate how appropriate interventions may be successfully adopted and implemented within different contexts, an organising framework of implementation is employed.

soft systems approach is used for the evaluation of different interventions and policies by mapping interactions and consequences using qualitative and quantitative data. To connect these multi-level and multidisciplinary approaches, the Consolidated Framework for Implementation Research (CFIR) is used as an overarching organising framework as it facilitates understanding of processes of introduction and management of change within a complex healthcare system or pathway and allows for examination of behaviours.

WP3: Intervention design and implementation: Consolidated Framework for Implementation Research (CFIR) analysis

Scoping literature review for interventions implemented and/or evaluated. Outputs from WP1&2 will provide a comprehensive assessment of the ‘outer’ and ‘inner’ contexts including existing interventions in the study sites. For any new interventions, co-design workshops will provide an assessment of contextual fit. Pilot implementation will be carried out over a six-month period providing proof of concept data and variables for WP4.

Expected impact

  1. To identify ways of reducing overuse, underuse and misuse of antibiotics, improving quality of care and reducing waste of healthcare resources;
  2. To promote the efficient design of services by finding solutions along the patient pathway for patients undergoing surgery;
  3. In the long-term, to contribute to a reduction in costs to patients and society;
  4. To build research capacity in low- and middle-income countries and the tools to design and evaluate solutions