Project Title: Enabling and generating cell type specific maps of genome regulation using TIP-seq
Supervisor: Dr Nathan Skene, Dr Alexi Nott, Dr Maria Weinert
Location: Level 7, Sir Michael Uren Hub, White City Campus, 86 Wood Lane, W12 0BZ
About Me
I am a PhD student in Dr Nathan Skene’s group within the UK Dementia Research Institute centre at Imperial College London. Before relocating to London, I worked in the Genomics Core at the Centre for PanorOmic Sciences at the University of Hong Kong, where I developed a strong interest in genomic and epigenomic research. I later joined the Skene Lab as a Research Assistant, contributing to the development of new genomic methods to study gene regulation. This experience motivated me to continue my research journey as a PhD student within the group.
Qualifications
- 2012-2016: BSc in Biochemistry, the University of Hong Kong
- 2016-2017: MSc in Forensic Science, King’s College London
Research Interests
My research focuses on understanding cell type-specific gene regulation and developing methods to better profile the regulatory genome. I am particularly interested in applying such approaches to microglia, the key cell type implicated in Alzheimer’s disease. By generating detailed maps of genome regulation in microglia, I aim to uncover how epigenetic changes contribute to the development of Alzheimer’s disease. Ultimately, this knowledge may help identify new therapeutic targets and guide future treatment strategies.
Presentations and Conferences
Connectome 2024, poster presentation
Contact Details
Email: c.leung@imperial.ac.uk
LinkedIn: jade-leung-9b6a7124a
