Project Title: Bioinformatics problems for single-cell genomics
Supervisor: Dr. Nathan Skene, Professor Paul Matthews
Location: Sir Michael Uren Hub, White City Campus
About me
I am a PhD student at the UK Dementia Research Institute at Imperial College, London, investigating what single-cell RNA sequencing can tell us about the rate of progression of Alzheimer’s Disease. Before starting my PhD, I worked for a year at the University of Oxford’s NDM, as a Scientific Software Developer. My focus here was on neuroimaging and using FMRIB’s Software Library to carry out various types of image processing, including image normalisation and creating a QC platform to test the suitability of images for further analyses. Working in a medical setting at Oxford motivated me to search for a PhD in a similar field, and thus I started exploring the possibilities within Bioinformatics, which then lead to me looking into the programme at Imperial. Prior to my work at Oxford, I completed my integrated master’s (MSci) degree in Mathematics at Imperial College, London. My focus here was on Statistics, Applied Mathematics and Machine Learning.
Qualifications
MSci in Mathematics (2016-2020)
Research Interests
Applications of Statistics in single-cell genomics problems
Contact details
Email: salman.fawad16@imperial.ac.uk
LinkedIn: salman-fawad-464bb231
How temperature and circadian rhythms intersect to regulate a protein shown to protect against neurodegeneration
A new study led by Dr Marco Brancaccio (UK DRI at Imperial) and Dr Marieke Hoekstra (former UK DRI at Imperial, now VIB-KU Leuven Center for Brain & Disease Research) offers a deeper insight into how a neuroprotective pathway is regulated both by temperature and the body clock. This research, published in the journal PNAS, could open up new therapeutic avenues for neurodegenerative disease. Read more on the UK DRI website
Introducing Cynthia Sandor: Pioneering earlier detection of Parkinson’s
Dr Cynthia Sandor, former Emerging Leader at the UK DRI at Cardiff, joins the UK DRI at Imperial as a Group Leader, where she will be tackling early diagnosis of Parkinson’s.
With a background in genetics, Dr Sandor uses computational methods to bring greater understanding to the underlying molecular mechanisms of Parkinson’s. Read more about Cynthia's work on the UK DRI website.
