Dr Maria Papathanasiou

This webinar will be held on zoom. The stucture of the event will be a presentation followed by audience Q&A. Please register to be sent the joining instructions. You can pre-submit questions for the Q&A section when registering.

This webinar is part of the series

Vaccines: Development, Manufacturing and Distribution

The theme discussed in this webinar will be:

Digital Tools in Bioprocess Design and Optimisation

Abstract

Biopharmaceutical manufacturing is challenged by high manufacturing costs and large amount of waste. The complex nature of bioprocesses and measurement unavailability are some of the key challenges of process control. This results in trial-and-error experiments in traditional process development which may be costly and inefficient. Next generation bioprocesses necessitate agility and robustness against variabilities in the end-to-end operation. In that respect, computer modelling solutions can be key for the design of flexible operation and effective process optimisation. In this work, we develop a framework for process space identification using high-fidelity models to obtain a process map relating process inputs and parameters to the main Key Performance Indicators (KPIs). We showcase different methodologies for mapping the process space and assess them based on their accuracy and reliability.

Biography

Dr Maria Papathanasiou

Lecturer (Assistant Professor) in Centre for Process Systems Engineering (CPSE) Dept. of Chemical Engineering

Dr Maria Papathanasiou is a Lecturer (Assistant Professor) at the Department of Chemical Engineering, Imperial College London. She holds a PhD degree in Process Systems Engineering from the Department of Chemical Engineering at Imperial College London and an MSc from the same department. She completed her undergraduate studies at the School of Chemical Engineering, National Technical University of Athens and she conducted her Diploma Thesis in Food Process Engineering at the Technical University of Berlin. Dr Papathanasiou’s research focuses on the development of Process Systems Engineering tools (modelling, optimisation and control) with application to: (a) personalised medicine (from discovery to delivery), (b) biomanufacturing and (c) food systems engineering.

More events in the “Vaccines: Development, Manufacturing and Distribution” Series

About The Institute for Molecular Science and Engineering

The Institute for Molecular Science and Engineering (IMSE) is one of Imperial College London’s Global Institutes, drawing on the strength of its four faculties to address some of the grand challenges facing the world today. The Institute’s activities are focused on tackling problems where molecular innovation plays an important role.

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