This webinar will be held on zoom. The structure of the event will be a presentation followed by audience Q&A. Please register to be sent the joining instructions. You can pre-submit questions for the Q&A section when registering.
This webinar is part of the series
Molecular Level Understanding is Crucial for Targeted Drug Delivery in the Brain
The theme discussed in this webinar will be:
Antibody Discovery vs Neurodegeneration
Abstract
Dr Aprile is a new UKRI Future Leaders Fellow in the Department of Chemistry. His research, which combines chemical biology and biophysics, focuses on the development of antibodies as research and clinical tools. In particular, Dr Aprile applies high-throughput discovery methods to develop novel biomolecules to understand how the complex environment of the brain chemically modifies and modulates neurotoxic protein aggregates, called amyloids, which are a hallmark of many forms of dementia. Dr Aprile obtained his PhD from the University of Milano-Bicocca (Italy) and was previously a Senior Research Fellow of the Alzheimer’s Society in the Department of Chemistry at the University of Cambridge, where he developed antibodies to inhibit amyloid aggregation.
Biography
Dr Francesco Antonio Aprile
Faculty of Natural Sciences, Department of Chemistry, Future Leadership Fellow
Dr Aprile is a new UKRI Future Leaders Fellow in the Department of Chemistry. His research, which combines chemical biology and biophysics, focuses on the development of antibodies as research and clinical tools. In particular, Dr Aprile applies high-throughput discovery methods to develop novel biomolecules to understand how the complex environment of the brain chemically modifies and modulates neurotoxic protein aggregates, called amyloids, which are a hallmark of many forms of dementia. Dr Aprile obtained his PhD from the University of Milano-Bicocca (Italy) and was previously a Senior Research Fellow of the Alzheimer’s Society in the Department of Chemistry at the University of Cambridge, where he developed antibodies to inhibit amyloid aggregation.
Other webinars in the Molecular Level Understanding is Crucial for Targeted Drug Delivery in the Brain series
- 30 November 16.00 Biomechanical and biochemical aspects of infusion-based targeted drug delivery in brain Dr. Asad Jamal (Department of Mechanical Engineering)
- 14 December 14.00 Nanoparticles for treatment of Tuberculous Meningitis Professor. Alexandra Porter (Department of Materials) and Dr. Alessandra Pinna (Department of Materials)
- 18 January 16.00 Antibody Discovery vs Neurodegeneration Dr Francesco Antonio Aprile (Department of Chemistry)
- 25 January 16.00 Noninvasive drug delivery to the brain using short pulses of ultrasound Dr. James Choi (Department of Bioengineering)
- 1 February 16.00 Development of the bacteria viruses, bacteriophage, into a delivery technology for therapeutic nucleic acids against cancer and other human diseases Professor Amin Hajitou (Department of Brain Sciences)
- 8 February 16.00 Professor. Daniele Dini (Department of Mechanical Engineering) and Professor. Ferdinando Rodrigues y Baena (Department of Mechanical Engineering)
About The Institute for Molecular Science and Engineering
The Institute for Molecular Science and Engineering (IMSE) is one of Imperial College London’s Global Institutes, drawing on the strength of its four faculties to address some of the grand challenges facing the world today. The Institute’s activities are focused on tackling problems where molecular innovation plays an important role.
If you have any questions about accessibility requirements please email Leah Adamson (IMSE Events Officer) on l.adamson@imperial.ac.uk