Participate in a trial

Key information

We are looking for participants with Alzheimer's disease to take part in a non invasive brain stimulation study. The study involves 16 visits to the Imperial College London White City campus, during which you will be asked to complete a series of cognitive tasks while we stimulate the hippocampus and record brain activity.

For further information and to get involved, please contact Research Assistants Julia Borella (julia.borella21@imperial.ac.uk) or Kaarin Sabad (k.sabad@imperial.ac.uk).

Alzheimer's disease study

Summary of the study

We are looking for participants with Alzheimer's disease or Mild Cognitive Impairment (65+)  to take part in a study investigating the use of non-invasive deep brain stimulation and its effects on the hippocampus, a structure deep within the brain that is responsible for memory function and often the first area where the disruptions of normal brain activity occur in Alzheimer's disease. 

The purpose of this study is to assess the short-term effects of temporal interference (TI) stimulation on the brain activity and cognitive performance of people with early stage Alzheimer's disease. 

What does the study involve?

After expressing interest, you will be invited for a telephone pre-screening call to determine your initial suitability for the study. If successful, you will be enrolled and invited to attend a screening visit and 16 study visits spanning 3 months at Imperial College London's Clinical Research Facility (ICRF) at Hammersmith Hospital. 

Screening visit

Before commencing on the study, you will be invited for a screening visit at the ICRF, with the aim to determine your eligibility for the study. At the screening visit, a detailed description of the study will be provided and any questions you may have will be answered. You will then be familiarised with the technology we use to measure your brain activity and stimulate the brain. This will be followed by an interview with the lead clinician on our study.

Study visits

TBC

Am I eligible to take part?

You will be able to take part in the study if:

  • You are aged 65-100 years
  • You have a diagnosis of Alzheimer's disease or Mild Cognitive Impairment and have been experiencing difficulties with your memory
  • You have not suffered from traumatic brain injury, epilepsy, strokes or frequent migraines
  • You have no metal or electronic objects in your body, such as a pacemaker
  • You do not have any severe skin lesions on our scalp
  • You do not suffer from anxiety in confined spaces (claustrophobia) such that you cannot tolerate an MRI scan

Will I be reimbursed for taking part?

Travel to and from the study site will be arranged by the study team and you will receive a £10/hour for each study visit.

How can I get involved?

Please email Research Assistants Julia Borella (julia.borella21@imperial.ac.uk) or Kaarin Sabad (k.sabad@imperial.ac.uk) to express your interest.