BibTex format
@article{Hill:2024:10.1101/2024.05.16.24307504,
author = {Hill, V and Cleemput, S and Fonseca, V and Tegally, H and Brito, AF and Gifford, R and Tran, VT and Kien, DTH and Huynh, T and Yacoub, S and Dieng, I and Ndiaye, M and Balde, D and Diagne, MM and Faye, O and Salvato, R and Wallau, GL and Gregianini, TS and Godinho, FMS and Vogels, CBF and Breban, MI and Leguia, M and Jagtap, S and Roy, R and Hapuarachchi, C and Mwanyika, G and Giovanetti, M and Alcantara, LCJ and Faria, NR and Carrington, CVF and Hanley, KA and Holmes, EC and Dumon, W and de, Oliveira T and Grubaugh, ND},
doi = {10.1101/2024.05.16.24307504},
journal = {medRxiv},
title = {A new lineage nomenclature to aid genomic surveillance of dengue virus.},
url = {http://dx.doi.org/10.1101/2024.05.16.24307504},
year = {2024}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Dengue virus (DENV) is currently causing epidemics of unprecedented scope in endemic settings and expanding to new geographical areas. It is therefore critical to track this virus using genomic surveillance. However, the complex patterns of viral genomic diversity make it challenging to use the existing genotype classification system. Here we propose adding two sub-genotypic levels of virus classification, named major and minor lineages. These lineages have high thresholds for phylogenetic distance and clade size, rendering them stable between phylogenetic studies. We present an assignment tool to show that the proposed lineages are useful for regional, national and sub-national discussions of relevant DENV diversity. Moreover, the proposed lineages are robust to classification using partial genome sequences. We provide a standardized neutral descriptor of DENV diversity with which we can identify and track lineages of potential epidemiological and/or clinical importance. Information about our lineage system, including methods to assign lineages to sequence data and propose new lineages, can be found at: dengue-lineages.org.
AU - Hill,V
AU - Cleemput,S
AU - Fonseca,V
AU - Tegally,H
AU - Brito,AF
AU - Gifford,R
AU - Tran,VT
AU - Kien,DTH
AU - Huynh,T
AU - Yacoub,S
AU - Dieng,I
AU - Ndiaye,M
AU - Balde,D
AU - Diagne,MM
AU - Faye,O
AU - Salvato,R
AU - Wallau,GL
AU - Gregianini,TS
AU - Godinho,FMS
AU - Vogels,CBF
AU - Breban,MI
AU - Leguia,M
AU - Jagtap,S
AU - Roy,R
AU - Hapuarachchi,C
AU - Mwanyika,G
AU - Giovanetti,M
AU - Alcantara,LCJ
AU - Faria,NR
AU - Carrington,CVF
AU - Hanley,KA
AU - Holmes,EC
AU - Dumon,W
AU - de,Oliveira T
AU - Grubaugh,ND
DO - 10.1101/2024.05.16.24307504
PY - 2024///
TI - A new lineage nomenclature to aid genomic surveillance of dengue virus.
T2 - medRxiv
UR - http://dx.doi.org/10.1101/2024.05.16.24307504
UR - https://www.ncbi.nlm.nih.gov/pubmed/38798319
ER -