In this section
@article{Hancock:2024:10.1016/j.pt.2024.04.016,
author = {Hancock, PA and Ochomo, E and Messenger, LA},
doi = {10.1016/j.pt.2024.04.016},
journal = {Trends in Parasitology},
pages = {604--618},
title = {Genetic surveillance of insecticide resistance in African Anopheles populations to inform malaria vector control},
url = {http://dx.doi.org/10.1016/j.pt.2024.04.016},
volume = {40},
year = {2024}
}
TY - JOUR
AB - Insecticide resistance in malaria vector populations poses a major threat to malaria control, which relies largely on insecticidal interventions. Contemporary vector-control strategies focus on combatting resistance using multiple insecticides with differing modes of action within the mosquito. However, diverse genetic resistance mechanisms are present in vector populations, and continue to evolve. Knowledge of the spatial distribution of these genetic mechanisms, and how they impact the efficacy of different insecticidal products, is critical to inform intervention deployment decisions. We developed a catalogue of genetic-resistance mechanisms in African malaria vectors that could guide molecular surveillance. We highlight situations where intervention deployment has led to resistance evolution and spread, and identify challenges in understanding and mitigating the epidemiological impacts of resistance.
AU - Hancock,PA
AU - Ochomo,E
AU - Messenger,LA
DO - 10.1016/j.pt.2024.04.016
EP - 618
PY - 2024///
SN - 1471-4922
SP - 604
TI - Genetic surveillance of insecticide resistance in African Anopheles populations to inform malaria vector control
T2 - Trends in Parasitology
UR - http://dx.doi.org/10.1016/j.pt.2024.04.016
VL - 40
ER -
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