BibTex format
@article{Bratcher:2019:10.12688/wellcomeopenres.15362.2,
author = {Bratcher, HB and Rodrigues, CMC and Finn, A and Wootton, M and Cameron, JC and Smith, A and Heath, P and Ladhani, S and Snape, MD and Pollard, AJ and Cunningham, R and Borrow, R and Trotter, C and Gray, SJ and Maiden, MCJ and MacLennan, JM},
doi = {10.12688/wellcomeopenres.15362.2},
journal = {Wellcome Open Res},
title = {UKMenCar4: A cross-sectional survey of asymptomatic meningococcal carriage amongst UK adolescents at a period of low invasive meningococcal disease incidence.},
url = {http://dx.doi.org/10.12688/wellcomeopenres.15362.2},
volume = {4},
year = {2019}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Carriage of Neisseria meningitidis, the meningococcus, is a prerequisite for invasive meningococcal disease (IMD), a potentially devastating infection that disproportionately afflicts infants and children. Humans are the sole known reservoir for the meningococcus, and it is carried asymptomatically in the nasopharynx of ~10% of the population. Rates of carriage are dependent on age of the host and social and behavioural factors. In the UK, meningococcal carriage has been studied through large, multi-centre carriage surveys of adolescents in 1999, 2000, and 2001, demonstrating carriage can be affected by immunisation with the capsular group C meningococcal conjugate vaccine, inducing population immunity against carriage. Fifteen years after these surveys were carried out, invasive meningococcal disease incidence had declined from a peak in 1999. The UKMenCar4 study was conducted in 2014/15 to investigate rates of carriage amongst the adolescent population during a period of low disease incidence. The protocols and methodology used to perform UKMenCar4, a large carriage survey, are described here.
AU - Bratcher,HB
AU - Rodrigues,CMC
AU - Finn,A
AU - Wootton,M
AU - Cameron,JC
AU - Smith,A
AU - Heath,P
AU - Ladhani,S
AU - Snape,MD
AU - Pollard,AJ
AU - Cunningham,R
AU - Borrow,R
AU - Trotter,C
AU - Gray,SJ
AU - Maiden,MCJ
AU - MacLennan,JM
DO - 10.12688/wellcomeopenres.15362.2
PY - 2019///
SN - 2398-502X
TI - UKMenCar4: A cross-sectional survey of asymptomatic meningococcal carriage amongst UK adolescents at a period of low invasive meningococcal disease incidence.
T2 - Wellcome Open Res
UR - http://dx.doi.org/10.12688/wellcomeopenres.15362.2
UR - https://www.ncbi.nlm.nih.gov/pubmed/31544158
VL - 4
ER -