BibTex format
@article{Dennis:2025:10.1101/2025.03.24.644828,
author = {Dennis, TPW and Sulieman, JE and Abdin, M and Ashine, T and Asmamaw, Y and Eyasu, A and Simma, EA and Zemene, E and Negash, N and Kochora, A and Assefa, M and Elzack, HS and Dagne, A and Lukas, B and Bulto, MG and Enayati, A and Nikpoor, F and Al-Nazawi, AM and Al-Zahrani, MH and Khaireh, BA and Kayed, S and Abdi, A-IA and Allan, R and Ashraf, F and Pignatelli, P and Morris, M and Nagi, SC and Lucas, ER and Hernandez-Koutoucheva, A and Doumbe-Belisse, P and Epstein, A and Brown, R and Wilson, AL and Reynolds, AM and Sherrard-Smith, E and Yewhalaw, D and Gadisa, E and Malik, E and Kafy, HT and Donnelly, MJ and Weetman, D},
doi = {10.1101/2025.03.24.644828},
journal = {bioRxiv},
title = {The origin, invasion history and resistance architecture of Anopheles stephensi in Africa.},
url = {http://dx.doi.org/10.1101/2025.03.24.644828},
year = {2025}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - The invasion of Africa by the Asian urban malaria vector, Anopheles stephensi, endangers 126 million people across a rapidly urbanising continent where malaria is primarily a rural disease. Control of An. stephensi requires greater understanding of its origin, invasion dynamics, and mechanisms of widespread resistance to vector control insecticides. We present a genomic surveillance study of 551 An. stephensi sampled across the invasive and native ranges in Africa and Asia. Our findings support a hypothesis that an initial invasion from Asia to Djibouti seeded separate incursions to Sudan, Ethiopia, and Yemen before spreading inland, aided by favourable temperature, vegetation cover, and human transit conditions. Insecticide resistance in invasive An. stephensi is conferred by detoxification genes introduced from Asia. These findings, and a companion genomic data catalogue, will form the foundation of an evidence base for surveillance and management strategies for An. stephensi.
AU - Dennis,TPW
AU - Sulieman,JE
AU - Abdin,M
AU - Ashine,T
AU - Asmamaw,Y
AU - Eyasu,A
AU - Simma,EA
AU - Zemene,E
AU - Negash,N
AU - Kochora,A
AU - Assefa,M
AU - Elzack,HS
AU - Dagne,A
AU - Lukas,B
AU - Bulto,MG
AU - Enayati,A
AU - Nikpoor,F
AU - Al-Nazawi,AM
AU - Al-Zahrani,MH
AU - Khaireh,BA
AU - Kayed,S
AU - Abdi,A-IA
AU - Allan,R
AU - Ashraf,F
AU - Pignatelli,P
AU - Morris,M
AU - Nagi,SC
AU - Lucas,ER
AU - Hernandez-Koutoucheva,A
AU - Doumbe-Belisse,P
AU - Epstein,A
AU - Brown,R
AU - Wilson,AL
AU - Reynolds,AM
AU - Sherrard-Smith,E
AU - Yewhalaw,D
AU - Gadisa,E
AU - Malik,E
AU - Kafy,HT
AU - Donnelly,MJ
AU - Weetman,D
DO - 10.1101/2025.03.24.644828
PY - 2025///
TI - The origin, invasion history and resistance architecture of Anopheles stephensi in Africa.
T2 - bioRxiv
UR - http://dx.doi.org/10.1101/2025.03.24.644828
UR - https://www.ncbi.nlm.nih.gov/pubmed/40196515
ER -