BibTex format
@article{Galue:2025:10.1177/15303667251383703,
author = {Galue, J and de, Souza WM and Torres-Cosme, R and Lezcano-Coba, C and Tesh, RB and Guzman, H and Weaver, SC and Capitan-Barrios, Z and Valderrama, A and Samudio, R and Vittor, AY and Vasilakis, N and Carrera, LC and Donnelly, CA and Faria, NR and Carrera, J-P},
doi = {10.1177/15303667251383703},
journal = {Vector-Borne and Zoonotic Diseases},
pages = {749--760},
title = {Contrasting ecological patterns of Venezuelan equine encephalitis and Madariaga viruses in small mammal and mosquito populations from two enzootic regions of Panama},
url = {http://dx.doi.org/10.1177/15303667251383703},
volume = {25},
year = {2025}
}
RIS format (EndNote, RefMan)
TY - JOUR
AB - Background:Understanding enzootic cycles is key to arbovirus control. Rodents are primary reservoirs of Venezuelan equine encephalitis virus (VEEV), whereas the vertebrate host of Madariaga virus (MADV) remains unknown. Culex (Melanoconion) mosquitoes are considered primary vectors. We studied small mammals and mosquito ecology in the Darién province and Panamá Oeste province, two enzootic regions of Panama. Additional alphavirus seroprevalence was assessed in small mammals.Methods:Small mammals were trapped using Sherman and Tomahawk traps, and blood samples were tested for MADV and VEEV neutralizing antibodies using plaque reduction neutralization test and attempt viral isolation and generic alphavirus RT-PCR from small mammal tissues. Mosquitoes were collected concurrently using Centers for Disease Control and Prevention (CDC) light, Trinidad, and resting traps. Diversity and similarity were analyzed using standard ecological indices.Results:We sampled 599 small mammals (16 species). MADV seroprevalence was highest in Los Pavitos (9.0%) and restricted to Darién; VEEV was more widespread, peaking in El Cacao (27.3%) and El Real (20.4%). Oryzomys couesi and Transandinomys bolivaris showed elevated MADV seroprevalence; T. bolivaris and Proechimys semispinosus had higher VEEV seroprevalence. Among 4118 mosquitoes, Coquillettidia venezuelensis was most abundant. El Real had the highest species richness and diversity. Geographic proximity influenced community similarity.Conclusions:Spatial differences in host and vector communities may reflect distinct transmission patterns of MADV and VEE. These findings could contribute to better understanding of alphavirus ecology and potentially inform public health strategies in endemic regions.
AU - Galue,J
AU - de,Souza WM
AU - Torres-Cosme,R
AU - Lezcano-Coba,C
AU - Tesh,RB
AU - Guzman,H
AU - Weaver,SC
AU - Capitan-Barrios,Z
AU - Valderrama,A
AU - Samudio,R
AU - Vittor,AY
AU - Vasilakis,N
AU - Carrera,LC
AU - Donnelly,CA
AU - Faria,NR
AU - Carrera,J-P
DO - 10.1177/15303667251383703
EP - 760
PY - 2025///
SN - 1530-3667
SP - 749
TI - Contrasting ecological patterns of Venezuelan equine encephalitis and Madariaga viruses in small mammal and mosquito populations from two enzootic regions of Panama
T2 - Vector-Borne and Zoonotic Diseases
UR - http://dx.doi.org/10.1177/15303667251383703
VL - 25
ER -