In this section
@article{Ferguson:1997:10.1098/rstb.1997.0063,
author = {Ferguson, NM and Donnelly, CA and Woolhouse, ME and Anderson, RM},
doi = {10.1098/rstb.1997.0063},
journal = {Philos Trans R Soc Lond B Biol Sci},
pages = {803--838},
title = {The epidemiology of BSE in cattle herds in Great Britain. II. Model construction and analysis of transmission dynamics},
url = {http://dx.doi.org/10.1098/rstb.1997.0063},
volume = {352},
year = {1997}
}
TY - JOUR
AB - Mathematical model that describe the key processes determining the pattern of the bovine spongiform encephalopathy (BSE) epidemic in British cattle are derived that allow for infection from feed as well as maternal and direct horizontal transmission. Heterogeneous susceptibility classes are also incorporated into the analysis. Maximum likelihood methods are used to estimate parameters and to obtain confidence intervals from available experimental and epidemiological data. A comprehensive sensitivity analysis of all model parameters and distributional assumptions is presented. Additional validation is provided by fitting the model to independent data collected in Northern Ireland. Model estimates and predictions based on BSE case data for Great Britain and Northern Ireland, together with their implications, are reviewed, and future research priorities discussed.
AU - Ferguson,NM
AU - Donnelly,CA
AU - Woolhouse,ME
AU - Anderson,RM
DO - 10.1098/rstb.1997.0063
EP - 838
PY - 1997///
SN - 0962-8436
SP - 803
TI - The epidemiology of BSE in cattle herds in Great Britain. II. Model construction and analysis of transmission dynamics
T2 - Philos Trans R Soc Lond B Biol Sci
UR - http://dx.doi.org/10.1098/rstb.1997.0063
UR - http://www.ncbi.nlm.nih.gov/pubmed/9279898
VL - 352
ER -
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