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Conference paperWan Y, Jauneikaite E, Gao L, et al., 2025,
Neonatal intensive care units as a driver and reservoir of invasive infections: an example of the emerging Staphylococcus capitis multidrug-resistant NRCS-A clone
, Publisher: ELSEVIER SCI LTD, ISSN: 1201-9712 -
Journal articleHan SM, Shiino T, Masuda S, et al., 2025,
Phylogenetic Study of Local Patterns Influenza A(H3N2) Virus Transmission in a Semi-Isolated Population in a Remote Island in Japan Between 2011 and 2013
, INFLUENZA AND OTHER RESPIRATORY VIRUSES, Vol: 19, ISSN: 1750-2640 -
Journal articleNathvani R, Cavanaugh A, Suel E, et al., 2025,
Measurement of urban vitality with time-lapsed street-view images and object-detection for scalable assessment of pedestrian-sidewalk dynamics
, ISPRS JOURNAL OF PHOTOGRAMMETRY AND REMOTE SENSING, Vol: 221, Pages: 251-264, ISSN: 0924-2716- Cite
- Citations: 3
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Journal articleSun D, Ellepola G, Herath J, et al., 2025,
Climatically Specialized Lineages of Batrachochytrium dendrobatidis, and its Likely Asian Origins.
, Ecohealth, Vol: 22, Pages: 91-107Chytridiomycosis is a wildlife disease that has caused significant declines in amphibian populations and species extinctions worldwide. Asia, where the causal pathogens Batrachochytrium dendrobatidis (Bd) and B. salamndrivorans (Bsal) originated, has not witnessed mass die-offs. It is hypothesized that Asian amphibians may have evolved immunity to clinical Batrachochytrium infection, but this has not been explored in depth due to limited knowledge of endemic lineages and infection patterns. We investigated Bd's genetic diversity and infection patterns in south China's Guangxi region using the internal transcribed spacer (ITS) marker and nested PCR. Across the 17 forest sites studied (N = 1088 individuals; 1012 adults and 76 tadpoles), the overall prevalence of Bd infection was 4.74% in adult individuals and 5.26% in tadpoles. We found seven new haplotypes, four of which were closely related to the BdASIA-1 lineage from South Korea. The most prevalent haplotype (genetically similar to BdASIA-3) was found in 11 out of 15 infected species, including a salamander with non-lethal skin lesions. A generalized linear model of our environmental data indicates that Bd infection is correlated with mean temperature of the warmest quarter and elevation, with higher infection prevalence associated with lower temperature and relatively higher elevation in southern China. Our findings suggest significant undiscovered genetic diversity of Asian Bd lineages in this region. Longer-term studies are required to further investigate Bd diversity, prevalence, seasonality, and impact on native species and populations in Southern China and across the region of origin in Asia.
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Journal articlePickles M, Gregson S, Moorhouse L, et al., 2025,
Association of life-course events with predictors of HIV risk behaviour and HIV acquisition in Manicaland, Zimbabwe: a longitudinal analysis of a population cohort
, LANCET HIV, Vol: 12, Pages: e214-e222, ISSN: 2352-3018- Cite
- Citations: 2
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Conference paperRodgus J, Getino M, Wan Y, et al., 2025,
Understanding the genomic landscape of Klebsiella pneumoniae: insights into bacteraemia across North-West London hospitals between April 2020-December 2021
, Publisher: ELSEVIER SCI LTD, ISSN: 1201-9712 -
Journal articlePenn MJ, Scheidwasser N, Khurana MP, et al., 2025,
Phylo2Vec: A Vector Representation for Binary Trees
, SYSTEMATIC BIOLOGY, Vol: 74, Pages: 250-266, ISSN: 1063-5157- Cite
- Citations: 1
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Journal articlePetrie J, Hay JA, Srimokla O, et al., 2025,
Enhanced testing can substantially improve defense against several types of respiratory virus pandemic
, EPIDEMICS, Vol: 50, ISSN: 1755-4365 -
Journal articleTornimbene B, Leiva Rioja ZB, Aderinola O, et al., 2025,
Pathways to strengthening the epidemic intelligence workforce
, BMC Proceedings, Vol: 19, ISSN: 1753-6561The evolving landscape of public health surveillance demands a proficient and diverse workforce adept in data science and analysis. This report summarises discussions from the third session of the WHO Pandemic and Epidemic Intelligence Innovation Forum, focusing on workforce readiness and technological advancements in epidemic intelligence. The forum emphasizes the necessity of multidisciplinary surveillance teams equipped with advanced data skills. Digital tools play a transformative role in data collection and analysis, enabling real-time tracking, integration, and interpretation of diverse data sources. However, effective surveillance relies on inclusive representation and skill development. Collaborative surveillance and interdisciplinary training programs were emphasized as critical pathways to enhance workforce capacity, decision-making, and equity in public health. Case studies from Nigeria, Korea, the UK, and Colombia showcase the role of digital tools and contextual expertise in addressing surveillance gaps. Sustained institutional support, cross-sector partnerships, and investments in data literacy and workforce development are pivotal for creating resilient and inclusive public health systems.
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Journal articleDelbaje E, Pontes L, Rhodes J, et al., 2025,
Aspergillus fumigatus mitogenomes and their influence on azole-resistant and -susceptible populations
, npj Antimicrobials and Resistance, Vol: 3, ISSN: 2731-8745The role of the fungal mitochondria goes far beyond energy metabolism. The genomes of 318 Aspergillus fumigatus clinical and environmental isolates from different geographic origins were analyzed aiming to study the mitochondrial sequences from populations sensitive and resistant to azoles. Our results show that A. fumigatus mitogenomic sequences are very conserved and only show variation in small intergenic regions and one intronic sequence in the cox3 gene. Furthermore, a genome-wide association analysis of accessory mitochondrial genes revealed potential mitochondria-based genotypes that may interact synergistically with the ergosterol biosynthesis pathway to confer the resistant phenotype. This includes a mutation in the AMID-like mitochondrial oxidoreductase (aifA, AFUA_3G01290) and the absence of the mitochondrial carrier protein (pet8, AFUA_8G01400). Deletion of these genes did not change the azole-susceptibility but increased the azole-persistence, suggesting mitochondrial genes could be involved in azole-persistence. Our work opens new hypotheses for the involvement of mitochondria in A. fumigatus azole-resistance.
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