Publications

Search or filter publications

Search publications Search

Filter by type:

Filter by publication type

• Book
• Book chapter
• Conference paper
• Journal article
• Other
• Patent
• Poster
• Report
• Scholarly edition
• Software
• Thesis dissertation
• Working paper

Filter by year:

Filter from 2026202520242023202220212020201920182017201620152014201320122011201020092008200720062005200420032002200120001999199819971996199519941993199219911990198919881987198619851984198319821981198019791978197719761975197419731972 to Filter to 2026202520242023202220212020201920182017201620152014201320122011201020092008200720062005200420032002200120001999199819971996199519941993199219911990198919881987198619851984198319821981198019791978197719761975197419731972

---

Search results

• Journal article
  Balloux F, Handley L-JL, Jombart T, Liu H, Manica Aet al., 2009,

  Climate shaped the worldwide distribution of human mitochondrial DNA sequence variation

  , PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, Vol: 276, Pages: 3447-3455, ISSN: 0962-8452
  • Cite
  • Citations: 117
• Conference paper
  van Elsland S, van der Hoeven M, Joshi S, Doak Cet al., 2009,

  Owning a pressure cooker is associated with better food security in HIV/AIDS affected households in Aurangabad, india

  , International Congress of Nutrition
  • Cite
• Conference paper
  van der Hoeven M, van Elsland S, Joshi S, Doak Cet al., 2009,

  Household food security and child nutritional status in HIV/AIDS affected Indian Families

  , International Congress of Nutrition 2009
  • Cite
• Journal article
  Hancock PA, 2009,

  Combining fungal biopesticides and insecticide-treated bednets to enhance malaria control

  , PLoS Computational Biology, Vol: 5, Pages: 1-11, ISSN: 1553-734X

  In developing strategies to control malaria vectors, there is increased interest in biological methods that do not cause instant vector mortality, but have sublethal and lethal effects at different ages and stages in the mosquito life cycle. These techniques, particularly if integrated with other vector control interventions, may produce substantial reductions in malaria transmission due to the total effect of alterations to multiple life history parameters at relevant points in the life-cycle and transmission-cycle of the vector. To quantify this effect, an analytically tractable gonotrophic cycle model of mosquito-malaria interactions is developed that unites existing continuous and discrete feeding cycle approaches. As a case study, the combined use of fungal biopesticides and insecticide treated bednets (ITNs) is considered. Low values of the equilibrium EIR and human prevalence were obtained when fungal biopesticides and ITNs were combined, even for scenarios where each intervention acting alone had relatively little impact. The effect of the combined interventions on the equilibrium EIR was at least as strong as the multiplicative effect of both interventions. For scenarios representing difficult conditions for malaria control, due to high transmission intensity and widespread insecticide resistance, the effect of the combined interventions on the equilibrium EIR was greater than the multiplicative effect, as a result of synergistic interactions between the interventions. Fungal biopesticide application was found to be most effective when ITN coverage was high, producing significant reductions in equilibrium prevalence for low levels of biopesticide coverage. By incorporating biological mechanisms relevant to vectorial capacity, continuous-time vector population models can increase their applicability to integrated vector management.

  • Abstract
  • Publisher Web Link
  • Cite
• Conference paper
  Chindelevitch L, Liao C-S, Berger B, 2009,

  Local optimization for global alignment of protein interaction networks

  , Pacific Symposium on Biocomputing 2010, Publisher: World Scientific, Pages: 123-132

  We propose a novel algorithm, PISwap, for computing global pairwise alignments of protein interaction networks, based on a local optimization heuristic that has previously demonstrated its effectiveness for a variety of other NP-hard problems, such as the Traveling Salesman Problem. Our algorithm begins with a sequence-based network alignment and then iteratively adjusts the alignment by incorporating network structure information. It has a worst-case pseudo-polynomial running-time bound and is very efficient in practice. It is shown to produce improved alignments in several well-studied cases. In addition, the flexible nature of this algorithm makes it suitable for different applications of network alignments. Finally, this algorithm can yield interesting insights into the evolutionary history of the compared species.

  • Abstract
  • Cite
• Journal article
  Stothard JR, French MD, Khamis IS, Basanez M-G, Rollinson Det al., 2009,

  The epidemiology and control of urinary schistosomiasis and soil-transmitted helminthiasis in schoolchildren on Unguja Island, Zanzibar

  , TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, Vol: 103, Pages: 1031-1044, ISSN: 0035-9203
  • Cite
  • Citations: 75
• Journal article
  Murray KA, Skerratt LF, Speare R, McCallum Het al., 2009,

  Impact and Dynamics of Disease in Species Threatened by the Amphibian Chytrid Fungus, <i>Batrachochytrium dendrobatidis</i>

  , CONSERVATION BIOLOGY, Vol: 23, Pages: 1242-1252, ISSN: 0888-8892
  • Author Web Link
  • Cite
  • Citations: 127
• Journal article
  Boily M-C, Baggaley RF, Masse B, 2009,

  The role of heterosexual anal intercourse for HIV transmission in developing countries: are we ready to draw conclusions?

  , SEXUALLY TRANSMITTED INFECTIONS, Vol: 85, Pages: 408-410, ISSN: 1368-4973
  • Author Web Link
  • Cite
  • Citations: 20
• Journal article
  Mâsse BR, Boily M-C, Dimitrov1 D, Desai Ket al., 2009,

  Efficacy dilution in randomized placebo-controlled vaginal microbicide trials

  , Emerging themes in Epidemiology, Vol: 6

  BackgroundTo date different vaginal gel microbicides have been evaluated in phase 2b/3 trials, but none have demonstrated effectiveness for preventing HIV infection. Failure to demonstrate effectiveness however does not necessarily indicate that a product is truly inefficacious, as several sources of efficacy dilution may compromise our ability to identify products that may have been truly efficacious.MethodsFor four individual sources of dilution, we describe the dilution mechanisms and quantify the expected effectiveness. An overall expected effectiveness that combines all sources of dilution in a trial is derived as well.ResultsUnder conditions that have been observed in recent microbicide trials, the overall expected effectiveness assuming an active gel with true efficacy of 50% and 75% are in the range of [16%; 33%] and [28%; 50%], respectively, when considering the four major sources of dilution. In contrast the diluting effect due to adherence alone (assuming an adherence of 80%) leads to higher expected effectiveness, 40% and 60% assuming an active gel with true efficacy of 50% and 75%, respectively. Individual sources of dilution may demonstrate a small effect when evaluated independently, but the overall dilution effect in a trial with several sources of dilution can be quite substantial.ConclusionCurrently planned phase 2b/3 microbicide trials of new candidate vaginal microbicides are not immune from these shortcomings. A good understanding of dilution effects is necessary to properly interpret microbicide trial results and to identify products worthy of further development and evaluation. Greater attention should be devoted to reducing and assessing the impact of efficacy dilution and to carefully selecting the effect size in the design of future trials.

  • Abstract
  • Cite
• Journal article
  Sousa-Figueiredo JC, Basanez M-G, Khamis IS, Garba A, Rollinson D, Stothard JRet al., 2009,

  Measuring Morbidity Associated with Urinary Schistosomiasis: Assessing Levels of Excreted Urine Albumin and Urinary Tract Pathologies

  , PLOS NEGLECTED TROPICAL DISEASES, Vol: 3, ISSN: 1935-2735
  • Cite
  • Citations: 24

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.