CDT React - Student Publications

Aatikah Majid - Cohort 1 (Intake 2019)

"Radiolabelling Pt-based quadruplex DNA binders via click chemistry"

• Lo, R., Majid, A., Fruhwirth, G. O., & Vilar, R., 2022. Bioorganic & Medicinal Chemistry, 76, 117097. doi.org/10.1016/j.bmc.2022.117097

Hannah Broderick - Cohort 1 (Intake 2019)

"Visible Light Photoredox-Catalyzed Decarboxylative Alkylation of 3-Aryl-Oxetanes and Azetidines via Benzylic Tertiary Radicals and Implications of Benzylic Radical Stability"

• Dubois, M.A., Rojas, J.J., Sterling, A.J., Broderick, H.C., Smith, M.A., White, A.J., Miller, P.W., Choi, C., Mousseau, J.J., Duarte, F. and Bull, J.A., J. Org. Chem., 2023, DOI: 10.1021/acs.joc.3c00083

Joshua Davies - Cohort 1 (Intake 2019)

"Silicon compounds as stoichiometric coupling reagents for direct amidation"

• J. J. Davies, D. C. Braddock, P. D. Lickiss, Org. Biomol. Chem., 2021, 19, 6746-6760, doi.org/10.1039/D1OB01003D

"Methyltrimethoxysilane (MTM) as a Reagent for Direct Amidation of Carboxylic Acids"

• Braddock, D.C., Davies, J.J. and Lickiss, P.D., 2022. Methyltrimethoxysilane (MTM) as a Reagent for Direct Amidation of Carboxylic Acids. Organic letters, 24(5), pp.1175-1179.

Sean McCarthy - Cohort 1 (Intake 2019)

"Strategies for sustainable palladium catalysis"

• S. McCarthy, D. C. Braddock, J. D. E. T. Wilton-Ely, Coordin. Chem. Rev., 2021, 442, DOI: 10.1016/j.ccr.2021.213925.

"From waste to green applications: The use of recovered gold and palladium in catalysis”

• S. McCarthy, A. L. W. Jie, D. C. Braddock, A. Serpe, J. D. E. T. Wilton-Ely, Molecules, 2021, 26, DOI: 10.3390/molecules26175217.

"Homogeneous Gold Catalysis Using Complexes Recovered from Waste Electronic Equipment"

• McCarthy, S., Desaunay, O., Jie, A.L.W., Hassatzky, M., White, A.J., Deplano, P., Braddock, D.C., Serpe, A. and Wilton-Ely, J.D., ACS Sustainable Chemistry & Engineering, 2022, 10(48), doi.org/10.1021/acssuschemeng.2c04092

“Palladium complexes derived from waste as catalysts for C-H functionalisation and C-N bond formation”

• A. Jantan, G. Ekart, S. McCarthy, A. J. P. White, D. C. Braddock, A. Serpe, J. D. E. T. Wilton-Ely* Catalysts, 2024, 14, 295 [DOI: 10.3390/catal14050295]

Linden Schrecker - Cohort 1 (Intake 2019)

"Discovery of unexpectedly complex reaction pathways for the Knorr pyrazole synthesis via transient flow"

• L. Schrecker, J. Dickhaut, Christian Holtze, P. Staehle, M. Vranceanu, K. Hellgardt, K. K. Hii, React. Chem. Eng. 2023, 8, 41-46. DOI: 10.1039/D2RE00271J. 

"An efficient multiparameter method for the collection of chemical reaction data via ‘one-pot’ transient flow"

• L. Schrecker, J. Dickhaut, C. Holtze, P. Staehle, A. Weija, K. Hellgardt, K. K. Hii, React. Chem. Eng. 2023, 8, 3196-3202. DOI: 10.1039/D3RE00439B. 

“A Comparative Study of Transient Flow Rate Steps and Ramps for the Efficient Collection of Kinetic Data”

• Schrecker, J. Dickhaut, C. Holtze, P. Staehle, M. Vranceanu, A. Wieja, K. Hellgardt and K. K. Hii,* React. Chem. Eng, 2024, 9, 1077-1086. DOI: 10.1039/d3re00696d.

Filip Horvarth-Gerber - Cohort 1 (Intake 2019)

"Mass transport of Diazomethane across Teflon AF2400 membrane for scale-up development”

• Horvath-Gerber, K. K. Hii, C. Holtze, E. J. C. Deublein, K. Hellgardt, Org. Process Res. Dev. 2023, 27, 899-909. DOI: 10.1021/acs.oprd.3c00023.

Ben Lancaster - Cohort 1 (Intake 2019)

"Surmounting Byproduct Inhibition in an Intermolecular Catalytic Asymmetric Alkene Bromoesterification Reaction as Revealed by Kinetic Profiling”

• Braddock, D. C., Lancaster, B. M., Tighe, C. J., & White, A. The Journal of Organic Chemistry, 2023, DOI: https://doi.org/10.1021/acs.joc.3c00672

Matthew Takle - Cohort 1 (Intake 2019)

"A Flash Thermal Racemization Protocol for the Chemoenzymatic Dynamic Kinetic Resolution and Stereoinversion of Chiral Amines”

• Takle, M. J., Deadman, B. J., Hellgardt, K., Dickhaut, J., Wieja, A., & Hii, K. K. M. ACS Catalysis, 13(16), 10541-10546, 2023, DOI: https://doi.org/10.1021/acscatal.3c02859

Annabel Basford - Cohort 2 (Intake 2020)

"Streamlining the Automated Discovery of Porous Organic Cages"

• Basford, A., Bennett S., Xiao M., Turcani L., Allen J., Jelfs K., Greenaway R., ChemRxiv, November 2023

Sarah Patrick - Cohort 2 (Intake 2020)

"A Continuous Flow Process for the Defluorosilylation of HFC-23 and HFO-1234yf"

• S. L. Patrick, J. A. Bull, P. W. Miller, M. R. Crimmin, Org. Lett. 2024, 26, 40, 8605–8609

Harriet Judah - Cohort 2 (Intake 2020) [Blog]

"Chemical recycling: where one plastic’s trash is another plastic’s treasure"

Miguel Angel de Carvalho Servia - Cohort 3 (Intake 2021)

"The Automated Discovery of Kinetic Rate Models--Methodological Frameworks"

• Ángel de Carvalho Servia, M., Orson Sandoval, I., Hellgardt, K., Hii, K. K., Zhang, D. and del Rio Chanona, E.A., Digital Discovery, 2024 https://doi.org/10.1039/D3DD00212H

Friedrich Hastedt - Cohort 4 (Intake 2022)

“Investigating the Reliability and Interpretability of Machine Learning Frameworks for Chemical Retrosynthesis”

• Hastedt, R. M. Bailey, K. Hellgardt, S. N. Yaliraki, E. A. del Rio Chanona, and D. Zhang, Digital Discovery, 2024, 3, 1194-1212, DOI: 10.1039/D4DD00007