Browse through all publications from the Institute of Global Health Innovation, which our Patient Safety Research Collaboration is part of. This feed includes reports and research papers from our Centre. 


BibTex format

author = {Archer, SA and Pinto, A and Vuik, S and Bicknell, C and Faiz, O and Byrne, B and Johnston, M and Skapinakis, P and Athanasiou, T and Vincent, C and Darzi, A},
doi = {10.1097/SLA.0000000000002745},
journal = {Annals of Surgery},
pages = {95--101},
title = {Surgery, complications and quality of life: a longitudinal cohort study exploring the role of psychosocial factors},
url = {},
volume = {270},
year = {2019}

RIS format (EndNote, RefMan)

AB - Objective:To determine if psychosocial factors moderate the relationship between surgical complications and quality of life (QoL).Summary Background:Patients who experience surgical complications have significantly worse post-operative QoL than patients with an uncomplicated recovery. Psychosocial factors, such as coping style and level of social support influence how people deal with stressful events, but it is unclear if they impact on QoL following a surgical complication. These findings can inform the development of appropriate interventions that support patients post-operatively. Methods:This is a longitudinal cohort study; data were collected at pre-op, 1 month post-op, 4 months post-op and 12 months post-op. A total of 785 patients undergoing major elective gastro-intestinal, vascular or cardio-thoracic surgery were recruited from 28 National Health Service (NHS) sites in England and Scotland took part in the study.Results:Patients who experience major surgical complications report significantly reduced levels of physical and mental QoL (p<0.05) but they make a full recovery over time. Findings indicate that a range of psychosocial factors such as the use of humor as a coping style and the level of health care professional support may moderate the impact of surgical complications on QoL.Conclusion:Surgical complications alongside other socio-demographic and psychosocial factors contribute to changes in QoL; the results from this exploratory study suggest that interventions that increase the availability of healthcare professional support and promote more effective coping strategies prior to surgery may be useful, particularly in the earlier stages of recovery where QoL is most severely compromised. However, these relationships should be further explored in longitudinal studies that include other types of surgery and employ rigorous recruitment and follow up procedures.
AU - Archer,SA
AU - Pinto,A
AU - Vuik,S
AU - Bicknell,C
AU - Faiz,O
AU - Byrne,B
AU - Johnston,M
AU - Skapinakis,P
AU - Athanasiou,T
AU - Vincent,C
AU - Darzi,A
DO - 10.1097/SLA.0000000000002745
EP - 101
PY - 2019///
SN - 0003-4932
SP - 95
TI - Surgery, complications and quality of life: a longitudinal cohort study exploring the role of psychosocial factors
T2 - Annals of Surgery
UR -
UR -
VL - 270
ER -