Search or filter publications

Search publications Search

Filter by type:

Filter by publication type

• Book
• Book chapter
• Conference paper
• Journal article
• Patent
• Report
• Software

Filter by year:

Filter from 202220212020201920182017201620152014201320122011201020092008200720062005200420032002200120001999199819971996199519941993199219911990 to Filter to 202220212020201920182017201620152014201320122011201020092008200720062005200420032002200120001999199819971996199519941993199219911990

---

Search results

• Journal article
  Glor FP, Long Q, Hughes AD, Augst AD, Ariff B, Thom SAM, Verdonck PR, Xu XYet al., 2003,

  Reproducibility study of magnetic resonance image-based computational fluid dynamics prediction of carotid bifurcation flow

  , ANNALS OF BIOMEDICAL ENGINEERING, Vol: 31, Pages: 142-151, ISSN: 0090-6964
  • Author Web Link
  • Cite
  • Citations: 69
• Conference paper
  Papathanasopoulou P, Zhao SZ, Kohler U, Robertson MB, Long Q, Hoskins P, Xu XY, Marshall Iet al., 2003,

  MRI measurement of time-resolved wall shear stress vectors in a carotid bifurcation model, and comparison with CFD predictions

  , 10th Annual Meeting of the International-Society-for-Magnetic-Resonance-in-Medicine, Publisher: JOHN WILEY & SONS INC, Pages: 153-162, ISSN: 1053-1807
  • Author Web Link
  • Cite
  • Citations: 124
• Conference paper
  Ricard F, Brechtelsbauer C, Lawrence C, Xu Y, Pannier Aet al., 2003,

  Application of electrical resistance tomography technology to pharmaceutical processes

  , Pages: 701-706

  Recent developments in the use of non-intrusive, electrical measurements to interrogate mixing processes in batch vessels have triggered a joint GSK/Imperial College project aimed at assessing the applicability of Electrical Resistance Tomography (ERT) to pharmaceutical process development. A jacketed 3.5 L glass reactor was fitted with 64 platinum sensors arranged on 4 planes and linked to an ITS P2000 data acquisition system. Several vessel/stirrer configurations aimed at mimicking typical plant reactor geometries were investigated in connection with typical process scenarios in the pharmaceutical industry. Variations in local and bulk conductivity measurements were monitored, and the data obtained were compared with spectroscopic on-line monitoring information as well as kinetic and computational fluid dynamics modelling results. Very encouraging results were achieved for model and industrial processes. This approach shows promise for on-line control of process mixing performance as well as efficiency evaluation and optimisation of reactor geometries. This allows us to conclude that ERT is a valuable tool for the development of robust manufacturing processes for Active Pharmaceutical Ingredients.

  • Abstract
  • Cite
  • Citations: 11
• Journal article
  Augst AD, Barratt DC, Hughes AD, Thom SAM, Xu XYet al., 2003,

  Various issues relating to computational fluid dynamics simulations of carotid bifurcation flow based on models reconstructed from three-dimensional ultrasound images

  , PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, Vol: 217, Pages: 393-403, ISSN: 0954-4119
  • Author Web Link
  • Cite
  • Citations: 20
• Conference paper
  Glor FP, Ariff B, Augst AD, Barratt DC, Hughes AD, Thom SAM, Verdonck P, Xu XYet al., 2003,

  3D ultrasound-based CFD for carotid flow prediction: a reproducibility study

  , 2nd MIT Conference on Computational Fluid and Solid Mechanics, Publisher: ELSEVIER SCIENCE BV, Pages: 1701-1704
  • Author Web Link
  • Cite
  • Citations: 1
• Journal article
  Lee KW, Xu XY, 2002,

  Modelling of flow and wall behaviour in a mildly stenosed tube

  , MEDICAL ENGINEERING & PHYSICS, Vol: 24, Pages: 575-586, ISSN: 1350-4533
  • Author Web Link
  • Cite
  • Citations: 77
• Journal article
  Zhao SZ, Ariff B, Long Q, Hughes AD, Thom SA, Stanton AV, Xu XYet al., 2002,

  Inter-individual variations in wall shear stress and mechanical stress distributions at the carotid artery bifurcation of healthy humans

  , JOURNAL OF BIOMECHANICS, Vol: 35, Pages: 1367-1377, ISSN: 0021-9290
  • Author Web Link
  • Cite
  • Citations: 92
• Conference paper
  Glor FP, Long Q, Hughes AD, Augst AD, Ariff B, Thom SAM, Verdonck P, Xu XYet al., 2002,

  MR based CFD cardiovascular modelling: a reproducibility study on carotid blood flow

  , 7th Annual Meeting of the European-Council-for-Blood-Pressure-and-Cardiovascular-Research, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 582-582, ISSN: 0194-911X
  • Author Web Link
  • Cite
• Conference paper
  Ariff B, O'Neill A, Xu XY, Sever PS, Stanton AV, Hughes AD, Thom SMet al., 2002,

  Divergent effects on cardiac and carotid vascular remodelling in hypertensive subjects treated with candesartan cilexitil & atenolol.

  , 7th Annual Meeting of the European-Council-for-Blood-Pressure-and-Cardiovascular-Research, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 582-582, ISSN: 0194-911X
  • Author Web Link
  • Cite
• Conference paper
  Augst AD, Barratt DC, Hughes AD, Thom SA, Xu XYet al., 2002,

  CFD modeling of carotid bifurcation blood flow using 3D ultrasound

  , 7th Annual Meeting of the European-Council-for-Blood-Pressure-and-Cardiovascular-Research, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 571-571, ISSN: 0194-911X
  • Author Web Link
  • Cite
• Journal article
  Ariff B, Stanton A, Barratt D, Augst A, Glor F, Poulter N, Sever P, Xu Y, Hughes A, Thom SAet al., 2002,

  Comparison of the effects of antihypertensive treatment with angiotensin II blockade and beta-blockade on carotid wall structure and haemodynamics: protocol and baseline demographics

  , JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM, Vol: 3, Pages: 116-122, ISSN: 1470-3203
  • Author Web Link
  • Cite
  • Citations: 8
• Journal article
  Starmans-Kool MJ, Stanton AV, Zhao SZ, Xu XY, Thom SAM, Hughes ADet al., 2002,

  Measurement of hemodynamics in human carotid artery using ultrasound and computational fluid dynamics

  , JOURNAL OF APPLIED PHYSIOLOGY, Vol: 92, Pages: 957-961, ISSN: 8750-7587
  • Author Web Link
  • Cite
  • Citations: 11
• Journal article
  King E, Xu XY, Hughes AD, Long Q, Thom SA, Parker KHet al., 2002,

  Quantification of the non-planarity of the human carotid bifurcation

  , BIORHEOLOGY, Vol: 39, Pages: 419-424, ISSN: 0006-355X
  • Author Web Link
  • Cite
  • Citations: 5
• Journal article
  Long Q, Xu XY, Kohler U, Robertson MB, Marshall I, Hoskins Pet al., 2002,

  Quantitative comparison of CFD predicted and MRI measured velocity fields in a carotid bifurcation phantom

  , BIORHEOLOGY, Vol: 39, Pages: 467-474, ISSN: 0006-355X
  • Author Web Link
  • Cite
  • Citations: 21
• Journal article
  Köhler U, Marshall I, Robertson MB, Long Q, Xu XY, Hoskins PRet al., 2001,

  MRI measurement of wall shear stress vectors in bifurcation models and comparison with CFD predictions.

  , J Magn Reson Imaging, Vol: 14, Pages: 563-573, ISSN: 1053-1807

  Steady fluid flow was studied in a simple bifurcation model and in a physiologically realistic model of the human carotid bifurcation. Wall shear stress (WSS) vectors were calculated from phase-contrast (PC) magnetic resonance imaging (MRI) measurements of the velocity field. Velocity measurements in the inflow regions were also used as boundary conditions for computational fluid dynamics (CFD) calculations of WSS, which were compared with those derived from MRI alone. In regions of well-behaved flow, MRI and CFD estimates of WSS were in good general agreement. In regions of disturbed flow, for example near the bifurcation, the quality of the MRI measurements was sufficient for reliable calculation of WSS vectors when a sensitive surface coil was used. The combination of MRI and CFD would seem to be a powerful technique for the investigation of flow phenomena.

  • Abstract
  • Author Web Link
  • Cite
• Journal article
  Long Q, Xu XY, Ramnarine KV, Hoskins Pet al., 2001,

  Numerical investigation of physiologically realistic pulsatile flow through arterial stenosis

  , JOURNAL OF BIOMECHANICS, Vol: 34, Pages: 1229-1242, ISSN: 0021-9290
  • Author Web Link
  • Cite
  • Citations: 134
• Journal article
  Augst AD, Barratt DC, Hughes AD, Thom SAM, Xu XYet al., 2001,

  CFD model of a human carotid artery bifurcation reconstructed from 3D ultrasound data

  , HYPERTENSION, Vol: 38, Pages: 977-977, ISSN: 0194-911X
  • Author Web Link
  • Cite
• Journal article
  Xu XY, Zhao SZ, Ariff B, Long Q, Hughes AD, Thorn SA, Stanton AVet al., 2000,

  Shear stress and mechanical forces in the walls of carotid arteries

  , HYPERTENSION, Vol: 36, Pages: 664-664, ISSN: 0194-911X
  • Author Web Link
  • Cite
• Journal article
  Zhao SZ, Zambanini A, Long Q, Xu XY, Hughes AD, Thom SAet al., 2000,

  Difference in anatomical features of the femoral artery between male and female

  , HYPERTENSION, Vol: 36, Pages: 666-666, ISSN: 0194-911X
  • Author Web Link
  • Cite
• Journal article
  Zhao SZ, Xu XY, Hughes AD, Thom SA, Stanton AV, Ariff B, Long Qet al., 2000,

  Blood flow and vessel mechanics in a physiologically realistic model of a human carotid arterial bifurcation

  , JOURNAL OF BIOMECHANICS, Vol: 33, Pages: 975-984, ISSN: 0021-9290
  • Author Web Link
  • Cite
  • Citations: 210

This data is extracted from the Web of Science and reproduced under a licence from Thomson Reuters. You may not copy or re-distribute this data in whole or in part without the written consent of the Science business of Thomson Reuters.