In this section
@article{Chong:2020:10.1002/cnm.3399,
author = {Chong, MY and Gu, B and Chan, BT and Ong, ZC and Xu, XY and Lim, E},
doi = {10.1002/cnm.3399},
journal = {International Journal for Numerical Methods in Biomedical Engineering},
pages = {1--22},
title = {Effect of intimal flap motion on flow in acute type B aortic dissection by using fluid-structure interaction.},
url = {http://dx.doi.org/10.1002/cnm.3399},
volume = {36},
year = {2020}
}
TY - JOUR
AB - A monolithic, fully coupled fluid-structure interaction (FSI) computational framework was developed to account for dissection flap motion in acute type B aortic dissection (TBAD). Analysis of results included wall deformation, pressure, flow, wall shear stress (WSS), von. Mises stress and comparison of hemodynamics between rigid wall and FSI models. Our FSI model mimicked realistic wall deformation that resulted in maximum compression of the distal true lumen (TL) by 21.4%. The substantial movement of intimal flap mostly affected flow conditions in the false lumen (FL). Flap motion facilitated more flow entering the FL at peak systole, with the TL to FL flow split changing from 88:12 in the rigid model to 83:17 in the FSI model. There was more disturbed flow in the FL during systole (5.8% FSI vs. 5.2% rigid) and diastole (13.5% FSI vs. 9.8% rigid), via a λ2 -criterion. The flap-induced disturbed flow near the tears in the FSI model caused an increase of local WSS by up to 70.0% during diastole. This resulted in a significant reduction in the size of low time-averaged WSS (TAWSS) regions in the FL (113.11 cm2 FSI vs. 177.44 cm2 rigid). Moreover, the FSI model predicted lower systolic pressure, higher diastolic pressure, and hence lower pulse pressure. Our results provided new insights into the possible impact of flap motion on flow in aortic dissections, which are particularly important when evaluating hemodynamics of acute TBAD. This article is protected by copyright. All rights reserved.
AU - Chong,MY
AU - Gu,B
AU - Chan,BT
AU - Ong,ZC
AU - Xu,XY
AU - Lim,E
DO - 10.1002/cnm.3399
EP - 22
PY - 2020///
SN - 1069-8299
SP - 1
TI - Effect of intimal flap motion on flow in acute type B aortic dissection by using fluid-structure interaction.
T2 - International Journal for Numerical Methods in Biomedical Engineering
UR - http://dx.doi.org/10.1002/cnm.3399
UR - https://www.ncbi.nlm.nih.gov/pubmed/32862487
UR - https://onlinelibrary.wiley.com/doi/full/10.1002/cnm.3399
UR - http://hdl.handle.net/10044/1/82960
VL - 36
ER -
Room 1M17, ACE Extension Building
Department of Chemical Engineering
Imperial College London, South Kensington Campus
London, SW7 2AZ, UK
Tel: +44 (0)207 594 2562