Professor Albert Hofman (Plenary Lecture)
Harvard Chan School of Public Health
“Why are epidemiologists so bad at epidemics? The case of Alzheimer's disease.”
Professor Sudha Seshadri
UT Health San Antonio
“Aging, Resilience, Multimorbidity and Dementia in the Oldest-Old”
Professor Neil Davies
University College London
“The causes of Alzheimer’s disease, Mendelian randomization: what do we know, and what next?”
Dr Verena Zuber
Imperial College London
“Single cell Mendelian Randomisation on human brain disease and behaviour”
Dr James Yarmolinsky
Imperial College London
“Genetically proxied drug target perturbation for dementia research”
Professor Arfan Ikram
Erasmus University Medical Centre
“What makes dementia research so difficult? A few methodological considerations”
Professor Ole Andreasson
University of Oslo
“Multimodal prediction of Alzheimer’s disease – opportunities in Nordic registry and biobank data”
How temperature and circadian rhythms intersect to regulate a protein shown to protect against neurodegeneration
A new study led by Dr Marco Brancaccio (UK DRI at Imperial) and Dr Marieke Hoekstra (former UK DRI at Imperial, now VIB-KU Leuven Center for Brain & Disease Research) offers a deeper insight into how a neuroprotective pathway is regulated both by temperature and the body clock. This research, published in the journal PNAS, could open up new therapeutic avenues for neurodegenerative disease. Read more on the UK DRI website
Introducing Cynthia Sandor: Pioneering earlier detection of Parkinson’s
Dr Cynthia Sandor, former Emerging Leader at the UK DRI at Cardiff, joins the UK DRI at Imperial as a Group Leader, where she will be tackling early diagnosis of Parkinson’s.
With a background in genetics, Dr Sandor uses computational methods to bring greater understanding to the underlying molecular mechanisms of Parkinson’s. Read more about Cynthia's work on the UK DRI website.