The MIM Lab develops robotic and mechatronics surgical systems for a variety of procedures.

Head of Group

Prof Ferdinando Rodriguez y Baena

B415C Bessemer Building
South Kensington Campus

+44 (0)20 7594 7046

⇒ X: @fmryb

 

What we do

The Mechatronics in Medicine Laboratory develops robotic and mechatronics surgical systems for a variety of procedures including neuro, cardiovascular, orthopaedic surgeries, and colonoscopies. Examples include bio-inspired catheters that can navigate along complex paths within the brain (such as EDEN2020), soft robots to explore endoluminal anatomies (such as the colon), and virtual reality solutions to support surgeons during knee replacement surgeries.

Why is it important

The integration of mechatronics into medicine addresses critical challenges in modern healthcare by enhancing the precision, safety, and efficiency of surgical procedures. Traditional surgeries often involve significant risks and extended recovery times. By developing robotic systems that offer greater accuracy and control, we aim to minimise these risks and reduce invasiveness. Our research contributes to the advancement of minimally invasive techniques, which are essential for improving patient outcomes and optimising healthcare resources. Furthermore, our work supports the training of the next generation of surgeons, equipping them with cutting-edge tools and methodologies that reflect the evolving landscape of medical technology.

How can it benefit patients

Patients stand to gain significantly from the innovations developed at the Mechatronics in Medicine Laboratory. Our robotic systems are designed to perform surgeries with enhanced precision, leading to fewer complications and faster recovery times. Minimally invasive procedures facilitated by our technologies result in less postoperative pain and reduced scarring, improving the overall patient experience. Additionally, the increased accuracy of our systems can lead to better surgical outcomes, such as more complete tumour removals or more precise joint replacements, thereby improving long-term health prospects. By pushing the boundaries of medical robotics, we strive to make advanced surgical care more accessible and effective for patients worldwide.

Meet the team

Citation

BibTex format

@article{Jamal:2021:10.1109/TBME.2020.3024117,
author = {Jamal, A and Mongelli, M and Vidotto, M and Madekurozwa, M and Bernardini, A and Overby, D and De, Momi E and Rodriguez, y Baena F and Sherwood, J and Dini, D},
doi = {10.1109/TBME.2020.3024117},
journal = {IEEE Transactions on Biomedical Engineering},
pages = {1229--1237},
title = {Infusion mechanisms in brain white matter and its dependence of microstructure: an experimental study of hydraulic permeability},
url = {http://dx.doi.org/10.1109/TBME.2020.3024117},
volume = {68},
year = {2021}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Objective: Hydraulic permeability is a topic of deep interest in biological materials because of its important role in a range of drug delivery-based therapies. The strong dependence of permeability on the geometry and topology of pore structure and the lack of detailed knowledge of these parameters in the case of brain tissue makes the study more challenging. Although theoretical models have been developed for hydraulic permeability, there is limited consensus on the validity of existing experimental evidence to complement these models. In the present study, we measure the permeability of white matter (WM) of fresh ovine brain tissue considering the localised heterogeneities in the medium using an infusion based experimental set up, iPerfusion. We measure the flow across different parts of the WM in response to applied pressures for a sample of specific dimensions and calculate the permeability from directly measured parameters. Furthermore, we directly probe the effect of anisotropy of the tissue on permeability by considering the directionality of tissue on the obtained values. Additionally, we investigate whether WM hydraulic permeability changes with post-mortem time. To our knowledge, this is the first report of experimental measurements of the localised WM permeability, showing the effect of axon directionality on permeability. This work provides a significant contribution to the successful development of intra-tumoural infusion-based technologies, such as convection-enhanced delivery (CED), which are based on the delivery of drugs directly by injection under positive pressure into the brain.
AU - Jamal,A
AU - Mongelli,M
AU - Vidotto,M
AU - Madekurozwa,M
AU - Bernardini,A
AU - Overby,D
AU - De,Momi E
AU - Rodriguez,y Baena F
AU - Sherwood,J
AU - Dini,D
DO - 10.1109/TBME.2020.3024117
EP - 1237
PY - 2021///
SN - 0018-9294
SP - 1229
TI - Infusion mechanisms in brain white matter and its dependence of microstructure: an experimental study of hydraulic permeability
T2 - IEEE Transactions on Biomedical Engineering
UR - http://dx.doi.org/10.1109/TBME.2020.3024117
VL - 68
ER -

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Bessemer Building
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Imperial College
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