The MIM Lab develops robotic and mechatronics surgical systems for a variety of procedures.

Head of Group

Prof Ferdinando Rodriguez y Baena

B415C Bessemer Building
South Kensington Campus

+44 (0)20 7594 7046

⇒ X: @fmryb

 

What we do

The Mechatronics in Medicine Laboratory develops robotic and mechatronics surgical systems for a variety of procedures including neuro, cardiovascular, orthopaedic surgeries, and colonoscopies. Examples include bio-inspired catheters that can navigate along complex paths within the brain (such as EDEN2020), soft robots to explore endoluminal anatomies (such as the colon), and virtual reality solutions to support surgeons during knee replacement surgeries.

Why is it important

The integration of mechatronics into medicine addresses critical challenges in modern healthcare by enhancing the precision, safety, and efficiency of surgical procedures. Traditional surgeries often involve significant risks and extended recovery times. By developing robotic systems that offer greater accuracy and control, we aim to minimise these risks and reduce invasiveness. Our research contributes to the advancement of minimally invasive techniques, which are essential for improving patient outcomes and optimising healthcare resources. Furthermore, our work supports the training of the next generation of surgeons, equipping them with cutting-edge tools and methodologies that reflect the evolving landscape of medical technology.

How can it benefit patients

Patients stand to gain significantly from the innovations developed at the Mechatronics in Medicine Laboratory. Our robotic systems are designed to perform surgeries with enhanced precision, leading to fewer complications and faster recovery times. Minimally invasive procedures facilitated by our technologies result in less postoperative pain and reduced scarring, improving the overall patient experience. Additionally, the increased accuracy of our systems can lead to better surgical outcomes, such as more complete tumour removals or more precise joint replacements, thereby improving long-term health prospects. By pushing the boundaries of medical robotics, we strive to make advanced surgical care more accessible and effective for patients worldwide.

Meet the team

Citation

BibTex format

@article{Jamal:2022:10.3390/ijms23063139,
author = {Jamal, A and Yuan, T and Galvan, S and Castellano, A and Riva, M and Secoli, R and Falini, A and Bello, L and Rodriguez, y Baena F and Dini, D},
doi = {10.3390/ijms23063139},
journal = {International Journal of Molecular Sciences},
pages = {3139--3139},
title = {Insights into infusion-based targeted drug delivery in brain: perspectives, challenges and opportunities},
url = {http://dx.doi.org/10.3390/ijms23063139},
volume = {23},
year = {2022}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - Targeted drug delivery in the brain is instrumental in the treatment of lethal brain diseases, such as glioblastoma multiforme, the most aggressive primary central nervous system tumour in adults. Infusion-based drug delivery techniques, which directly administer to the tissue for local treatment, as in convection-enhanced delivery (CED), provide an important opportunity; however, poor understanding of the pressure-driven drug transport mechanisms in the brain has hindered its ultimate success in clinical applications. In this review, we focus on the biomechanical and biochemical aspects of infusion-based targeted drug delivery in the brain and look into the underlying molecular level mechanisms. We discuss recent advances and challenges in the complementary field of medical robotics and its use in targeted drug delivery in the brain. A critical overview of current research in these areas and their clinical implications is provided. This review delivers new ideas and perspectives for further studies of targeted drug delivery in the brain.
AU - Jamal,A
AU - Yuan,T
AU - Galvan,S
AU - Castellano,A
AU - Riva,M
AU - Secoli,R
AU - Falini,A
AU - Bello,L
AU - Rodriguez,y Baena F
AU - Dini,D
DO - 10.3390/ijms23063139
EP - 3139
PY - 2022///
SN - 1422-0067
SP - 3139
TI - Insights into infusion-based targeted drug delivery in brain: perspectives, challenges and opportunities
T2 - International Journal of Molecular Sciences
UR - http://dx.doi.org/10.3390/ijms23063139
UR - https://www.mdpi.com/1422-0067/23/6/3139
VL - 23
ER -

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The Hamlyn Centre
Bessemer Building
South Kensington Campus
Imperial College
London, SW7 2AZ
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