Glowmance in a Chip: When Neurons Meet Vessel, Credit: Elisa Duregotti, Imperial College London, British Heart Foundation - Reflections of Research

NHLI is a world-leading centre for cardiovascular and respiratory research, addressing some of the most urgent global health challenges. Our researchers work across four interconnected areas to advance understanding of heart, lung and vascular disease, and develop new approaches to prevention, diagnosis and treatment.

Cardiovascular Research

researchers working in tissue culture hood

Cardiac Science

Heart disease remains one of the leading causes of death worldwide. Our research seeks to understand the mechanisms that drive cardiovascular disease and identify new approaches to prevention, diagnosis and treatment.

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coronary artery disease scan

Vascular Science

The vascular system plays a central role in human health, regulating blood flow, inflammation and coagulation. Our research explores how vascular function is maintained in health and how it becomes disrupted in disease.

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Respiratory Research

culture plates

Infections, Genetics and Environment

Respiratory disease is shaped by a complex interplay of infection, genetic susceptibility and environmental exposure. Our research investigates how these factors influence disease risk, progression and outcomes.

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spirometry

Inflammation and Repair

Respiratory disease is driven not only by its causes, but by how the body responds to injury, infection and environmental exposure. Our research focuses on the inflammatory and immune mechanisms that shape disease and influence tissue repair.

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