Citation

BibTex format

@article{Richards:1975,
author = {Richards, RJ and Hext, PM and Desai, R and Tetley, T and Hunt, J and Presley, R and Dodgson, KS},
journal = {Inhaled Part},
pages = {477--493},
title = {Chrysotile asbestos: biological reaction potential.},
url = {https://www.ncbi.nlm.nih.gov/pubmed/1244073},
volume = {4 Pt 2},
year = {1975}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Evidence is presented indicating that chrysotile asbestos induces rapid cellular ageing in lung fibroblast cultures. Depending on the dose of asbestos given to these cultures the formation of fibrous collagen is enhanced or suppressed. The reaction of chrysotile at the cellular and molecular level is discussed and is considered to be determined by the organic coating it receives or the manner in which the surface absorbed material is modified. Studies are included of the ability of chrysotile to adsorb and retain serum proteins, pulmonary surfactant and lysosomal enzymes. Finally, a critical appraisal is given of the theories accounting for chrysotile-induced fibrogenesis particularly related to the lung fibroblast system studied.
AU  - Richards,RJ
AU  - Hext,PM
AU  - Desai,R
AU  - Tetley,T
AU  - Hunt,J
AU  - Presley,R
AU  - Dodgson,KS
EP  - 493
PY  - 1975///
SN  - 0301-1577
SP  - 477
TI  - Chrysotile asbestos: biological reaction potential.
T2  - Inhaled Part
UR  - https://www.ncbi.nlm.nih.gov/pubmed/1244073
VL  - 4 Pt 2
ER  -
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