ThalesNano H-Cube Pro and Phoenix Flow Reactor

One H-Cube Pro and one Phoenix high temperature flow reactors (ThalesNano) for:

  • Reaction scale-up in flow
  • Homogeneous and heterogeneous flow systems
  • High temperature (up to 450 °C) and pressurre (up to 200 bar)
  • In-line analytics (e.g. ReactIR) for the study of reaction intermediates and hazardous processes
  • Automated column changer for up to 6 independently heated catalyst cartridges

ThalesNano logo

ThalesNano pictures


Vapourtec R-Series Flow Reactor

An R-Series Vapourtec system for liquid flow reactions comprising:

  • Fully acid resistant pump modules
  • Two piston pumps
  • Two peristaltic pumps feeding capable of delivering slurries and gasses
  • 4 reactor positions, independently controllable
  • Reaction temperature of -70 to 250 °C
  • Microreactors
  • UV LED reactor for photochemial reactions
  • Autosampler and fraction collector

Vapourtec

Vapourtec system


fReactor

A fReactor, system containing up to 5 small volume continuous stirred tank reactors connected in series.

  • 2 mL individual stage volume - up to 10 mL total volume
  • Up to 100 psi pressure
  • Works on a common stirrer hotplate
  • Good chemical compatibility (reactor materials: PEEK and toughened glass; tubings material: PTFE)

fReactor logo

fReactor


Uniqsis FlowSyn and FlowUV

A Uniqsis FlowSyn for liquid flow reactions with:

  • 2 high-pressure pump channels with reagent injectors (up to 10 mL/min)
  • 1 tubular reaction module (up to 260 °C and 100 bar)
  • 1 column heater

A Uniqsis FlowUV for in-line UV-Vis analysis

  • Flow cell is transparent PFA reaction tubing
  • Dip-probe for batch experiments available
  • Can be positioned virtually anywhere in the flow path
  • Up to 35 bar at room temperature
  • 220-1050nm pulsed Xenon source
  • Up to 5 user-selected wavelength real-time monitoring
  • Full spectrum mode or multiple fixed wavelength modes

uniqsis


H-Genie Hydrogen Generator

One H-genie high pressure – high flow rate Hgenerator for hydrogenation reactions in flow or in batch.

  • Pressure range 1-100 bar
  • Flow rate range 0.1-1 L/min
  • Hydrogen electrochemically generated from DI water
  • High purity hydrogen (99.99% at 100 bar)
  • Built-in safety features (hydrogen and water leak detectors, internal pressure test, …)
  • Monitors hydrogen uptake and logs exportable data
  • Different setting options for flow, batch and balloon

H-genie


Synple Capsule Chemistry

One Synple platform (on loan) which allows fully automated, capsule-based synthesis. Synthesise and purify chemicals at the click of a button, by only adding the starting materials, the right solvents and the desired cartridge for the target reaction.

Available reaction cartridges include:

  • Reductive amination
  • N-Etherocycle formation (SnAP)
  • PROTAC formation
  • Biotin Tags
  • Mitsunobu
  • Boc protection
  • Boc de-protection
  • Deoxyfluorination
  • Azide formation

Synple


To find out more about our continuous flow chemistry platforms, contact us at ROAR@imperial.ac.uk

Contact us

Director: Prof Mimi Hii

Email: roar@imperial.ac.uk

The Molecular Sciences Research Hub
Imperial College White City Campus
82 Wood Lane
W12 0BZ London


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