Designing novel imaging probes for targeting inflammatory lesions in brain disorders

Monocytes are circulating white blood cells that play important roles in the inflammatory response and in brain disease. The ability to detect and quantify monocytic accumulation will enable scientists to locate and identify inflammatory brain lesions but also will facilitate the development and testing of anti-inflammatory agents.

This cross-disciplinary project will involve an iterative cycle of synthetic inorganic/organic chemistry and biological/imaging validation and analysis, and aims to develop diagnostic probes and tools that can detect both acute and chronic inflammation using biomedical imaging, resulting in improved diagnostic markers for the clinic, aiding assessment of improvement/repair of brain function.

Student

Tamara Boltersdorf

Supervisors

Nick Long (Chemistry)
Second supervisor tbc