The Imperial Genomics Facility (IGF) is one of the core facilities of the Genetics and Genomics Research Theme of the NIHR Imperial BRC. It forms part of the Epigenomics and Disease Section of the Department of Medicine and provides infrastructure and services to support translational research, harnessing genome information to advance disease diagnostics, prognosis and treatment. We provide integrated support from experimental design to library preparation, sequencing, data generation and analysis. Our team of experienced laboratory scientists and bioinformaticians bring together multidisciplinary expertise to offer clinicians and scientists access to state-of-the-art genome sequencing technologies, high-performance computing resources and cutting edge bioinformatics analysis of genomic data.