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• Journal article
  Trotter C, Findlow J, Balmer P, Holland A, Barchha R, Hamer N, Andrews N, Miller E, Borrow Ret al., 2007,

  Seroprevalence of bactericidal and anti-outer membrane vesicle antibodies to <i>Neisseria meningitildis</i> group B in England

  , CLINICAL AND VACCINE IMMUNOLOGY, Vol: 14, Pages: 863-868, ISSN: 1556-6811
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  • Citations: 41
• Journal article
  Ster IC, Ferguson NM, 2007,

  Transmission Parameters of the 2001 Foot and Mouth Epidemic in Great Britain

  , PLOS ONE, Vol: 2, ISSN: 1932-6203
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  • Citations: 79
• Journal article
  White RG, Cooper BS, Kedhar A, Orroth KK, Biraro S, Baggaley RF, Whitworth J, Korenromp EL, Ghani A, Boily M-C, Hayes RJet al., 2007,

  Quantifying HIV-1 transmission due to contaminated injections

  , PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 104, Pages: 9794-9799, ISSN: 0027-8424
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  • Citations: 19
• Journal article
  Gras L, Kesselring AM, Griffin JT, van Sighem AI, Fraser C, Ghani AC, Miedema F, Reiss P, Lange JMA, de Wolf Fet al., 2007,

  CD4 cell counts of 800 cells/mm<SUP>3</SUP> or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm<SUP>3</SUP> or greater

  , JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES, Vol: 45, Pages: 183-192, ISSN: 1525-4135
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  • Citations: 132
• Journal article
  Gambhir M, Basanez M-G, Turner F, Kumaresan J, Grassly NCet al., 2007,

  Trachoma:: transmission, infection, and control

  , LANCET INFECTIOUS DISEASES, Vol: 7, Pages: 420-427, ISSN: 1473-3099
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  • Citations: 40
• Journal article
  Riley S, Wu JT, Leung GM, 2007,

  Optimizing the dose of pre-pandemic influenza vaccines to reduce the infection attack rate.

  , PLoS Med, Vol: 4, Pages: e218-e218
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• Journal article
  Riley S, 2007,

  Large-scale spatial-transmission models of infectious disease.

  , Science, Vol: 316, Pages: 1298-1301
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• Journal article
  Maxwell R, Trotter C, Verne J, Brown P, Gunnell Det al., 2007,

  Trends in admissions to hospital involving an assault using a knife or other sharp instrument, England, 1997-2005

  , JOURNAL OF PUBLIC HEALTH, Vol: 29, Pages: 186-190, ISSN: 1741-3842
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  • Citations: 34
• Journal article
  Grassly NC, Wenger J, Durrani S, 2007,

  Protective efficacy of a monovalent oral type 1 poliovirus vaccine: a case-control study (vol 369, pg 1356, 2007)

  , LANCET, Vol: 369, Pages: 1790-1790, ISSN: 0140-6736
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  • Citations: 5
• Journal article
  Collin SM, Baggaley RF, Pittrof R, Filippi Vet al., 2007,

  Could a simple antenatal package combining micronutritional supplementation with presumptive treatment of infection prevent maternal deaths in sub-Saharan Africa?

  , BMC Pregnancy Childbirth, Vol: 7

  BACKGROUND: Reducing maternal mortality is a key goal of international development. Our objective was to determine the potential impact on maternal mortality across sub-Saharan Africa of a combination of dietary supplementation and presumptive treatment of infection during pregnancy. Our aim was to demonstrate the importance of antenatal interventions in the fight against maternal mortality, and to stimulate debate about the design of an effective antenatal care package which could be delivered at the lowest level of the antenatal health system or at community level. METHODS: We collated evidence for the effectiveness of antenatal interventions from systematic reviews and controlled trials, and we selected interventions which have demonstrated potential to prevent maternal deaths. We used a model-based analysis to estimate the total reduction in maternal mortality in sub-Saharan Africa which could be achieved by combining these interventions into a single package, based on a WHO systematic review of causes of maternal deaths. RESULTS: Severe hypertensive disorders, puerperal sepsis and anemia are causes of maternal deaths which could be prevented to some extent by prophylactic measures during pregnancy. A package of pills comprising calcium and iron supplements and appropriate anti-microbial and anti-malarial drugs could reduce maternal mortality in sub-Saharan Africa by 8% (range <1% to 20%). This estimate is based on Cochrane Review estimates for the effectiveness of daily calcium supplements in reducing the risk of death/serious morbidity due to hypertensive disorders (RR = 0.80, 95% CI 0.65-0.97), anti-microbial prophylaxis in reducing the odds of puerperal sepsis/postpartum endometritis (OR = 0.49, 95% CI 0.23-1.06), anti-malarial prophylaxis in reducing the risk of severe antenatal anemia (RR = 0.62, 95% CI 0.50-0.78), and iron supplementation in reducing the risk of iron deficiency anemia at term (RR = 0.33, 95% CI 0.16-0.69). CONCLUSION: Maternal mortalit

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