Anaesthesia makes up the largest hospital speciality and has a huge role to play in nearly every aspect of any hospital from operating theatres to accident and emergency, to the labour ward, and to intensive care. Our research ranges from basic molecular research into mechanisms of anaesthesia to investigating the clinical impact of novel anaesthetic agents.
Our research covers the entirety of patient’s perioperative journey and through this, we aim to deliver the greatest impact. The section has been pioneering in the development of novel technologies to facilitate the delivery of anaesthetic agents and has also made pivotal in-roads into the mechanism of action of anaesthetic agents and their wider application to other diseases (such as their protective roles in brain injury and in cancer).
Research themes:
- Anaesthesia mechanisms and effects
- Brain and neuroprotection
- Cardiothoracic anaesthesia and transplantation
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Journal articleVizcaychipi MP, Lloyd DG, Wan Y, et al., 2011,
Xenon Pretreatment May Prevent Early Memory Decline after Isoflurane Anesthesia and Surgery in Mice
, PLOS ONE, Vol: 6, ISSN: 1932-6203- Author Web Link
- Cite
- Citations: 34
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Journal articleVizcaychipi M, Grover S, Zhuang L, et al.,
Xenon preconditioning attenuates cognitive decline after orthopaedic surgery under general anaesthesia in mice
, Anesthesia & Analgesia -
Journal articlePotapov E, Meyer D, Swaminathan M, et al., 2011,
Inhaled nitric oxide after left ventricular assist device implantation: A prospective, randomized, double-blind, multicenter, placebo-controlled trial
, JOURNAL OF HEART AND LUNG TRANSPLANTATION, Vol: 30, Pages: 870-878, ISSN: 1053-2498- Author Web Link
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- Citations: 84
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Journal articleBertok S, Wilson MR, Dorr AD, et al., 2011,
Characterization of TNF receptor subtype expression and signaling on pulmonary endothelial cells in mice
, AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, Vol: 300, Pages: L781-L789, ISSN: 1040-0605- Cite
- Citations: 22
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Journal articleVizcaychipi MP, Xu L, Barreto GE, et al., 2011,
Heat Shock Protein 72 Overexpression Prevents Early Postoperative Memory Decline after Orthopedic Surgery under General Anesthesia in Mice
, ANESTHESIOLOGY, Vol: 114, Pages: 891-900, ISSN: 0003-3022- Author Web Link
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- Citations: 39
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Journal articleGu J, Sun P, Zhao H, et al., 2011,
Dexmedetomidine provides renoprotection against ischemia-reperfusion injury in mice
, CRITICAL CARE, Vol: 15, ISSN: 1466-609X- Author Web Link
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- Citations: 204
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Conference paperBanks P, Franks NP, 2011,
The NMDA receptor glycine site mediates xenon neuroprotection against hypoxic/ischemic injury
, 25th International Symposium on Cerebral Blood Flow, Metabolism & Function, Barcelona -
Journal articlePac-Soo C, Lloyd DG, Vizcaychipi MP, et al., 2011,
Statins: The Role in the Treatment and Prevention of Alzheimer's Neurodegeneration
, JOURNAL OF ALZHEIMERS DISEASE, Vol: 27, Pages: 1-10, ISSN: 1387-2877- Author Web Link
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- Citations: 38
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Journal articleZhang L, Huang H, Cheng J, et al., 2011,
Pre-treatment with isoflurane ameliorates renal ischemic–reperfusion injury in mice
, Life Sciences, Vol: 88, Pages: 1102 - 1107-1102 - 1107, ISSN: 0024-3205 -
Journal articleWan Y, Xu J, Meng F, et al., 2010,
Cognitive decline following major surgery is associated with gliosis, β-amyloid accumulation, and τ phosphorylation in old mice
, CRITICAL CARE MEDICINE, Vol: 38, Pages: 2190-2198, ISSN: 0090-3493- Author Web Link
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- Citations: 135
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